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Anti-MAS1 Polyclonal Antibody

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货号 TMAB-08621

Anti-MAS1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MAS1。Anti-MAS1 Polyclonal Antibody 可用于 FCM。

Anti-MAS1 Polyclonal Antibody

Anti-MAS1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08621

Anti-MAS1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MAS1。Anti-MAS1 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-MAS1 Polyclonal Antibody is a Rabbit antibody targeting MAS1. Anti-MAS1 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP binding proteins and share a conserved structural motif, which is described as a '7 transmembrane segment' following the prediction that these hydrophobic segments form membrane spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth regulating pathway to bring about oncogenic effects.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MAS1
抗原种属
Human
基因名称
MAS1
基因ID
蛋白名称
Proto-oncogene Mas
Uniprot ID
功能
Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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