Lactoferrin

Name: Lactoferrin
Brand: TargetMol
SKU: T9790
Price: 255 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 99.86%

货号 T9790Cas号 936541-36-5

别名 Lactoferrin (Bovine)

Lactoferrin 由哺乳动物分泌，具有广泛的生物学作用，包括提高应用良好的益生菌菌株的耐寒性。

Lactoferrin

一键复制产品信息

很棒

纯度: 99.86%

货号 T9790 别名 Lactoferrin (Bovine)Cas号 936541-36-5

Lactoferrin 由哺乳动物分泌，具有广泛的生物学作用，包括提高应用良好的益生菌菌株的耐寒性。

规格	价格	库存
5 mg	¥ 255	现货
10 mg	¥ 359	现货
25 mg	¥ 582	现货
50 mg	¥ 855	现货
100 mg	¥ 1,270	现货
500 mg	¥ 3,320	现货

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纯度: 99.86%

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COA HPLC 产品操作手册

产品介绍

Lactoferrin AI Summary

Lactoferrin exhibits strong inhibitory activities against several receptors and transport mechanisms. It demonstrates a significant inhibition of the [Ca(2+)]-permeable GluR3 receptor at 79.7% and much lower activity against the [Ca(2+)]-impermeable Ionotropic glutamate receptor AMPA at 4.3%. It also inhibits the transport of [3H]spermidine into MDA-MB-231 (human breast cancer) cells with a Ki value of 190.0 nM, indicating potential anti-cancer properties through spermidine transport inhibition. Additionally, it is a potent inhibitor of GluA1, GluA3, and GluA4 receptor flop isoforms, with IC50 values of 40.0 nM, 30.0 nM, and significant inhibition rates of 88.0%, 96.0%, and 82.0% at 0.5 µM, respectively. However, it does not significantly inhibit GluA1A2 and GluA2A3 receptor flop isoforms. It also shows antagonist activity against rat GluK1, GluA1, and glutamate N1/2A receptors with IC50 values of 19.0 nM, 65.0 nM, and 1710.0 nM, respectively. In cell viability assays, Lactoferrin negatively impacts the growth rate of HEK293T and U2OS cells, with growth rates ranging from -0.96 to -1.0, but has variable effects on human fibroblast cells, with growth rates ranging from -1.0 to 0.85, suggesting a cell-specific bioactivity profile..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Lactoferrin is secreted by mammals and displays extensive biological effects including boosting the cold tolerance of a well-applied probiotic strain.
别名	Lactoferrin (Bovine)

化学信息

分子量	565.716
分子式	C₂₇H₄₇N₇O₆
CAS No.	936541-36-5
Smiles	NCCCNCCCCNCCC(=O)NCCCCCNC(=O)[C@H](CC(N)=O)NC(=O)Cc1ccc(O)cc1O
密度	1.195g/cm3

储存&溶解度

存储

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度信息

H2O: 128.75 mg/mL (227.59 mM), Sonication is recommended.

溶液配制表

H2O

	1mg	5mg	10mg	50mg
1 mM	1.7677 mL	8.8384 mL	17.6767 mL	88.3836 mL
5 mM	0.3535 mL	1.7677 mL	3.5353 mL	17.6767 mL
10 mM	0.1768 mL	0.8838 mL	1.7677 mL	8.8384 mL
20 mM	0.0884 mL	0.4419 mL	0.8838 mL	4.4192 mL
50 mM	0.0354 mL	0.1768 mL	0.3535 mL	1.7677 mL
100 mM	0.0177 mL	0.0884 mL	0.1768 mL	0.8838 mL