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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IFIH1 Antibody (6Q630)

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货号 TMAB-07509

Anti-IFIH1 Antibody (6Q630) 是一种 Rabbit 抗体，靶向 IFIH1。Anti-IFIH1 Antibody (6Q630) 可用于 WB,ICC/IF。

Anti-IFIH1 Antibody (6Q630)

Anti-IFIH1 Antibody (6Q630)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07509

Anti-IFIH1 Antibody (6Q630) 是一种 Rabbit 抗体，靶向 IFIH1。Anti-IFIH1 Antibody (6Q630) 可用于 WB,ICC/IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-IFIH1 Antibody (6Q630) is a Rabbit antibody targeting IFIH1. Anti-IFIH1 Antibody (6Q630) can be used in WB,ICC/IF.
Ig Type
IgG
克隆号
6Q630
反应种属
Human
应用WBICC/IF
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. May be found in the nucleus, during apoptosis.
组织特异性Widely expressed, at a low level. Expression is detected at slightly highest levels in placenta, pancreas and spleen and at barely levels in detectable brain, testis and lung.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and pro-inflammatory cytokines
抗原信息
免疫原
A synthesized peptide: human MDA5
抗原种属
Human
基因名称
IFIH1
基因ID
64135
蛋白名称
Interferon-induced helicase C domain-containing protein 1
Uniprot ID
Q9BYX4
功能
RNA helicase that, through its ATP-dependent unwinding of RNA, may function to promote message degradation by specific RNases. Seems to have growth suppressive properties. Involved in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade involving MAVS/IPS1, which results in the activation of NF-kappa-B, IRF3 and IRF7 and the induction of the expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). ATPase activity is specifically induced by dsRNA. Essential for the production of interferons in response to picornaviruses.
化学信息
分子量Theoretical: 117 kDa. Actual: 117 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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