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Anti-TLR5 Polyclonal Antibody
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产品编号 TMAB-01858
Anti-TLR5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TLR5。Anti-TLR5 Polyclonal Antibody 可用于 WB。
Anti-TLR5 Polyclonal Antibody
Anti-TLR5 Polyclonal Antibody
还可以产品编号 TMAB-01858
Anti-TLR5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TLR5。Anti-TLR5 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-TLR5 Polyclonal Antibody is a Rabbit antibody targeting TLR5. Anti-TLR5 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse (predicted:Rat) |
| 验证活性 | 1. Sample: Liver (Mouse) Lysate at 40 μg Ovary (Mouse) Lysate at 40 μg Primary: Anti-TLR5 (TMAB-01858) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 95 kDa Observed band size: 130 kDa 2. Sample: Raw264.7 (Mouse) Cell Lysate at 30 μg Hela (Human) Cell Lysate at 30 μg Primary: Anti-TLR5 (TMAB-01858) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 95 kDa Observed band size: 130 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein (By similarity). |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | The Toll like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin 1 receptor-associated kinase (IRAK) signaling pathway. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens. |
| 免疫原 | KLH conjugated synthetic peptide: mouse TLR5 |
| 抗原种属 | Mouse |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Receptors,Macrophage / Inflamm.,TLR Signaling |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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