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Anti-NGFR/p75NTR Antibody (2N149)

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Anti-NGFR/p75NTR Antibody (2N149)
产品编号 TMAC-03038
别名 神经生长因子

Anti-NGFR/p75NTR Antibody (2N149) 是一种 Rabbit 抗体，靶向 NGFR/p75NTR。Anti-NGFR/p75NTR Antibody (2N149) 可用于 WB,ICC/IF,IHC,IP。

Anti-NGFR/p75NTR Antibody (2N149)

Anti-NGFR/p75NTR Antibody (2N149)

Rating icon 还可以
Anti-NGFR/p75NTR Antibody (2N149)
产品编号 TMAC-03038 别名 神经生长因子

Anti-NGFR/p75NTR Antibody (2N149) 是一种 Rabbit 抗体，靶向 NGFR/p75NTR。Anti-NGFR/p75NTR Antibody (2N149) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-NGFR/p75NTR Antibody (2N149) is a Rabbit antibody targeting NGFR/p75NTR. Anti-NGFR/p75NTR Antibody (2N149) can be used in WB,ICC/IF,IHC,IP.
别名神经生长因子
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of NGFR p75 on human skeletal muscle lysates using anti-NGFR p75 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-NGFR p75 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-NGFR p75 antibody. Counter stained with hematoxylin.
4. ICC staining NGFR p75 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining NGFR p75 in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
IHC
IP
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The Trk oncogene encodes a membrane-spanning protein tyrosine kinase, gp140Trk, whose expression is restricted in vivo to neurons of the sensory spinal and cranial ganglia of neural crest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk A in neural cell lines and in embryonic dorsal root ganglia. Tyrosine phosphorylation of Trk by NGF is rapid, specific and occurs with picomolar quantities of factor, indicating that the response is mediated by physiological amounts of NGF, suggesting that Trk A participates in the primary signal transduction mechanism of NGF. An additional component of the Trk A receptor complex, NGFR p75, binds to the neurotrophic factors with low affinity but is required for efficient signaling. NGFR p75 accelerates Trk A activation and may recruit downstream effector molecules to the liganded complex.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P08138
化学信息
分子量Theoretical: 75 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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