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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-nNOS (Ser1417) Polyclonal Antibody

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货号 TMAB-11061

Anti-Phospho-nNOS (Ser1417) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-nNOS (Ser1417)。Anti-Phospho-nNOS (Ser1417) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-nNOS (Ser1417) Polyclonal Antibody

Anti-Phospho-nNOS (Ser1417) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11061

Anti-Phospho-nNOS (Ser1417) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-nNOS (Ser1417)。Anti-Phospho-nNOS (Ser1417) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-nNOS (Ser1417) Polyclonal Antibody is a Rabbit antibody targeting Phospho-nNOS (Ser1417). Anti-Phospho-nNOS (Ser1417) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Zebrafish,Xenopus laevis)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine. Note=In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity).
组织特异性Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3 is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in the brain, but not in the heart and adrenal gland.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011].
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human nNOS around the phosphorylation site of Ser1417
抗原种属
Human
基因名称
NOS1
基因ID
4842
蛋白名称
Nitric oxide synthase, brain
Uniprot ID
P29475
功能
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
化学信息
分子量Theoretical: 160 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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