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Anti-human CD22 Antibody (6Q298)

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货号 TMAB-07394

Anti-human CD22 Antibody (6Q298) 是一种 Mouse 抗体，靶向 human CD22。Anti-human CD22 Antibody (6Q298) 可用于 FCM。

Anti-human CD22 Antibody (6Q298)

Anti-human CD22 Antibody (6Q298)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07394

Anti-human CD22 Antibody (6Q298) 是一种 Mouse 抗体，靶向 human CD22。Anti-human CD22 Antibody (6Q298) 可用于 FCM。

规格价格库存数量
100 μg
¥ 1,865
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产品介绍

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产品描述
Anti-human CD22 Antibody (6Q298) is a Mouse antibody targeting human CD22. Anti-human CD22 Antibody (6Q298) can be used in FCM.
Ig Type
Mouse IgG1
克隆号
6Q298
反应种属
Human
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cell membrane; Single-pass type I membrane protein.
组织特异性B-lymphocytes.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4).
浓度1mg/ml
研究背景Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome. [provided by Alliance of Genome Resources, Nov 2021]
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD22
抗原种属
Human
基因名称
CD22
基因ID
933
蛋白名称
B-cell receptor CD22
Uniprot ID
P20273
功能
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
化学信息
分子量Theoretical: 91 kDa. Actual: 140 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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