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Anti-Lumican Antibody (8Y396)

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Anti-Lumican Antibody (8Y396)
产品编号 TMAY-01958
别名 SLRR2D, lumican, LDC

Anti-Lumican Antibody (8Y396) 是一种 Rabbit 抗体，靶向 Lumican。Anti-Lumican Antibody (8Y396) 可用于 ICC/IF。

Anti-Lumican Antibody (8Y396)
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Anti-Lumican Antibody (8Y396)

Rating icon 还可以
Anti-Lumican Antibody (8Y396)
产品编号 TMAY-01958 别名 SLRR2D, lumican, LDC

Anti-Lumican Antibody (8Y396) 是一种 Rabbit 抗体，靶向 Lumican。Anti-Lumican Antibody (8Y396) 可用于 ICC/IF。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-Lumican Antibody (8Y396) is a Rabbit antibody targeting Lumican. Anti-Lumican Antibody (8Y396) can be used in ICC/IF.
别名SLRR2D, lumican, LDC
Ig Type
Rabbit IgG
克隆号
8Y396
交叉反应
Human
验证活性
Immunofluorescence staining of Human LUM in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human LUM monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm.
应用
ICC/IF
推荐剂量
ICC-IF: 1:20-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Lumican / LUM (rh Lumican / LUM; TMPY-01680; NP_002336.1; Met1-Asn338).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Lumican, a prototypic leucine-rich proteoglycan with keratan sulfate side chains, is a major component of the cornea, dermal, and muscle connective tissues. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and is also present in the connective tissues of other organs and embryonic corneal stroma as a glycoprotein. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration, and tissue repair. lumican expressed in injured epithelium may modulate cell behavior such as adhesion or migration, thus contributing to corneal epithelial wound healing. Lumican plays a crucial role in the regulation of collagen assembly into fibrils in various connective tissues and serve as a definitive link between a necessity for lumican in the development of a highly organized collagenous matrix and corneal transparency.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human Lumican / LUM Protein (TMPY-01680)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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