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Anti-KI2LA/CD158F Polyclonal Antibody

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货号 TMAB-07996

Anti-KI2LA/CD158F Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KI2LA/CD158F。Anti-KI2LA/CD158F Polyclonal Antibody 可用于 WB。

Anti-KI2LA/CD158F Polyclonal Antibody

Anti-KI2LA/CD158F Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07996

Anti-KI2LA/CD158F Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KI2LA/CD158F。Anti-KI2LA/CD158F Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-KI2LA/CD158F Polyclonal Antibody is a Rabbit antibody targeting KI2LA/CD158F. Anti-KI2LA/CD158F Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human KI2LA
抗原种属
Human
基因名称
KIR2DL5A
基因ID
57292
蛋白名称
Killer cell immunoglobulin-like receptor 2DL5A
Uniprot ID
Q8N109
功能
Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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