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Anti-FOXO1A Antibody (2K180)

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货号 TMAB-06133

Anti-FOXO1A Antibody (2K180) 是一种 Rabbit 抗体,靶向 FOXO1A。Anti-FOXO1A Antibody (2K180) 可用于 WB。

Anti-FOXO1A Antibody (2K180)

Anti-FOXO1A Antibody (2K180)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06133

Anti-FOXO1A Antibody (2K180) 是一种 Rabbit 抗体,靶向 FOXO1A。Anti-FOXO1A Antibody (2K180) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍


生物活性
产品描述
Anti-FOXO1A Antibody (2K180) is a Rabbit antibody targeting FOXO1A. Anti-FOXO1A Antibody (2K180) can be used in WB.
Ig Type
IgG
克隆号
2K180
反应种属
Human
验证活性
25 μg total protein per lane of various lysates (see on figure) probed with FOXO1A monoclonal antibody, unconjugated (TMAB-06133) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Shuttles between cytoplasm and nucleus. Translocates to the nucleus upon oxidative stress induced phosphorylation at Ser-212 by STK4/MST1. Translocates to the nucleus upon phosphorylation of Thr-24, Ser-256 and Ser-322 by SGK1.
组织特异性Ubiquitous.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq].
抗原信息
免疫原
A synthesized peptide: human FOXO1
抗原种属
Human
基因名称
FOXO1
基因ID
蛋白名称
Forkhead box protein O1
Uniprot ID
功能
Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence. Triggers death of postmitotic neurons when phosphorylated by CDK1. Activates transcription of PMAIP1.
化学信息
分子量Theoretical: 72 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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