Name: Artemin Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPK-00109
Price: 343 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

5 μg

¥ 343

现货

10 μg

¥ 549

现货

20 μg

¥ 898

现货

50 μg

¥ 1,760

3日内发货

100 μg

¥ 2,960

现货

200 μg

¥ 5,350

5日内发货

500 μg

¥ 11,800

5日内发货

生物活性

产品描述	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored GDNF family receptors a (GFRa1, GFRa3) and RET receptor tyrosine kinase. The major mechanism of ARTN action is via binding to a non-signaling co-receptor. The major function of ARTN is to drive the molecule to induce migration and axonal projection from sympathetic neurons.
生物活性	Immobilized Human GFRA3, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human ARTN, hFc Tag with the EC50 of 0.17μg/ml determined by ELISA.
研究背景	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored GDNF family receptors a (GFRa1, GFRa3) and RET receptor tyrosine kinase. The major mechanism of ARTN action is via binding to a non-signaling co-receptor. The major function of ARTN is to drive the molecule to induce migration and axonal projection from sympathetic neurons.
种属	Human
表达系统	HEK293 Cells
标签	N-hFc
蛋白编号	Q5T4W7-1
蛋白构建	Ala108-Gly220
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 4 mM HCl (pH 2.8). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in 4mM HCl (pH2.8). The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	Neublastin, NBN, EVN, Enovin, ARTNE, ARTN, Artemin
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	39.3 kDa (predicted). Due to glycosylation, the protein migrates to 48-52 kDa based on Tris-Bis PAGE result.
颜色	White
物理性状	Lyophilized powder

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Artemin Protein, Human, Recombinant (hFc)

Artemin Protein, Human, Recombinant (hFc)

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