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Anti-THAP11 Antibody (8P657) 是一种 Mouse 抗体,靶向 THAP11。Anti-THAP11 Antibody (8P657) 可用于 WB,ICC,IHC,FCM。
Anti-THAP11 Antibody (8P657) 是一种 Mouse 抗体,靶向 THAP11。Anti-THAP11 Antibody (8P657) 可用于 WB,ICC,IHC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,985 | 5日内发货 | |
100 μL | ¥ 2,995 | 5日内发货 |
产品描述 | Anti-THAP11 Antibody (8P657) is a Mouse antibody targeting THAP11. Anti-THAP11 Antibody (8P657) can be used in WB,ICC,IHC,FCM. |
别名 | THAP domain-containing protein 11, THAP domain containing 11, THAP 11, Thap 11, THA11_HUMAN, RONIN, HRIHFB2206, CTG B45d, CTG B43a |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of THAP11 on Hela (1) and NTERA-2 (2) cell lysate using anti-THAP11 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-THAP11 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue using anti-THAP11 antibody. Counter stained with hematoxylin. 4. ICC staining THAP11 (green) and actin filaments (red) in NTERA-2 cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of Hela cells with THAP11 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple). |
应用 | |
推荐剂量 | WB: 1:500; IHC: 1:50-200; ICC: 1:100-500; FCM: 1:100-200 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
研究背景 | Members of the THAP (thanatos-associated protein) family of proteins contain a well conserved DNA-binding domain known as the THAP-type zinc finger motif. Proteins containing the THAP-type zinc finger motif are commonly involved in transcriptional regulation, cell-cycle control, apoptosis and chromatin modification. The THAP-type zinc finger domain is suggested to have similarities with the site-specific DNA-binding domain (DBD) of Drosophila P element transposase. THAP11 (THAP domain containing 11), also known as HRIHFB2206, is a 314 amino acid protein that belongs to the THAP11 family and contains one THAP-type zinc finger. Localizing to the nucleus and cytoplasm, THAP11 may act as a transcriptional repressor, playing a role in embryogenesis and pluripotency of embryonic stem cells by recruiting epigenetic modifiers. THAP11 interacts with HCF1 via a coiled coil domain. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 45, 75 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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