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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-APRT Polyclonal Antibody

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货号 TMAB-02789

Anti-APRT Polyclonal Antibody 是一种 Rabbit 抗体，靶向 APRT。Anti-APRT Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-APRT Polyclonal Antibody

Anti-APRT Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02789

Anti-APRT Polyclonal Antibody 是一种 Rabbit 抗体，靶向 APRT。Anti-APRT Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-APRT Polyclonal Antibody is a Rabbit antibody targeting APRT. Anti-APRT Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景APRT is a 180 amino acid protein that localizes to the cytoplasm and belongs to the purine/pyrimidine phosphoribosyltransferase family. Existing as a homodimer, APRT functions to catalyze the formation of inorganic pyrophosphate and AMP from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP), a reaction that is essential for both purine metabolism and AMP biosynthesis. Defects in the gene encoding APRT are the cause of APRT deficiency, also known as 2,8-dihydroxyadenine urolithiasis, which is an autosomal recessive disease that results in renal failure. The gene encoding APRT maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
抗原信息
免疫原
KLH conjugated synthetic peptide: human APRT
抗原种属
Human
基因名称
APRT
基因ID
353
蛋白名称
Adenine phosphoribosyltransferase
Uniprot ID
P07741
功能
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
化学信息
分子量Theoretical: 19 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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