购物车
- 全部删除
您的购物车当前为空
Anti-AXL Antibody-FITC (1F430)
还可以产品编号 TMAY-00553F
Anti-AXL Antibody-FITC (1F430) 是一种 FITC-conjugated Mouse 抗体，靶向 AXL。Anti-AXL Antibody-FITC (1F430) 可用于 FCM。
Anti-AXL Antibody-FITC (1F430)
Anti-AXL Antibody-FITC (1F430)
还可以产品编号 TMAY-00553F
Anti-AXL Antibody-FITC (1F430) 是一种 FITC-conjugated Mouse 抗体，靶向 AXL。Anti-AXL Antibody-FITC (1F430) 可用于 FCM。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-AXL Antibody-FITC (1F430) is a FITC-conjugated Mouse antibody targeting AXL. Anti-AXL Antibody-FITC (1F430) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 1F430 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human AXL expression on DU145 cells. Cells were stained with FITC-conjugated anti-Human AXL. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multiple cell types. Axl functions in dampening the immune response, regulating cytokine secretion, clearing apoptotic cells and debris, and maintaining cell survival. Axl is upregulated in various disease states, such as in the cuprizone toxicity-induced model of demyelination and in multiple sclerosis (MS) lesions, suggesting that it plays a role in disease pathogenesis. Axl expression correlates with poor prognosis in several cancers. Axl mediates multiple oncogenic phenotypes and activation of these RTKs constitutes a mechanism of chemoresistance in a variety of solid tumors. Axl contributes to cell survival, migration, invasion, metastasis and chemosensitivity justify further investigation of Axl as novel therapeutic targets in cancer. The receptor tyrosine kinase AXL is thought to play a role in metastasis. The soluble AXL receptor as a therapeutic candidate agent for treatment of metastatic ovarian cancer. GAS6/AXL targeting as an effective strategy for inhibition of metastatic tumor progression in vivo. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human AXL Protein (TMPY-01601) |
| 抗原种属 | Human |
| 研究领域 | Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-AXL Antibody-FITC (1F430) | purchase Anti-AXL Antibody-FITC (1F430) | Anti-AXL Antibody-FITC (1F430) cost | order Anti-AXL Antibody-FITC (1F430)
嗨！有任何问题？点我咨询
评论内容