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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Frizzled 9 Polyclonal Antibody

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货号 TMAB-06172

Anti-Frizzled 9 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Frizzled 9。Anti-Frizzled 9 Polyclonal Antibody 可用于 WB,ELISA。

Anti-Frizzled 9 Polyclonal Antibody

Anti-Frizzled 9 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06172

Anti-Frizzled 9 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Frizzled 9。Anti-Frizzled 9 Polyclonal Antibody 可用于 WB,ELISA。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍

生物活性
产品描述
Anti-Frizzled 9 Polyclonal Antibody is a Rabbit antibody targeting Frizzled 9. Anti-Frizzled 9 Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBELISA
推荐剂量
WB: 1:500-2000; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
组织特异性Expressed predominantly in adult and fetal brain, testis, eye, skeletal muscle and kidney. Moderately expressed in pancreas, thyroid, adrenal cortex, small intestine and stomach. Detected in fetal liver and kidney.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
Recombinant Protein: human FZD9 protein
抗原种属
Human
基因名称
FZD9
基因ID
8326
蛋白名称
Frizzled-9
Uniprot ID
O00144
功能
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
化学信息
分子量Theoretical: 62 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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