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PTPRB Protein, Human, Recombinant (His)

PTPRB Protein, Human, Recombinant (His)

产品编号 TMPH-02010

PTPRB Protein, Human, Recombinant (His) is expressed in Yeast.

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PTPRB Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
20 μg ¥ 1,470 20日内发货
100 μg ¥ 2,780 20日内发货
500 μg ¥ 7,700 20日内发货
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: PTPRB Protein, Human, Recombinant (His) (TMPH-02010)
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生物活性
技术参数
产品性质
产品描述 PTPRB Protein, Human, Recombinant (His) is expressed in Yeast.
种属 Human
表达系统 P. pastoris (Yeast)
标签 N-6xHis
蛋白编号 P23467
氨基酸序列 RQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH
蛋白构建 1643-1997 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 43.4 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin.

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Keywords

recombinant recombinant-proteins proteins protein

 

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