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Anti-IDH1 Monoclonal Antibody (9A285) 是一种 Mouse 抗体,靶向 IDH1。Anti-IDH1 Monoclonal Antibody (9A285) 可用于 WB,IF,FCM。
别名 PICD, IDPC, IDP, IDH, IDCD, HEL-S-26, HEL-216
Anti-IDH1 Monoclonal Antibody (9A285) 是一种 Mouse 抗体,靶向 IDH1。Anti-IDH1 Monoclonal Antibody (9A285) 可用于 WB,IF,FCM。

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| 产品描述 | Anti-IDH1 Monoclonal Antibody (9A285) is a Mouse antibody targeting IDH1. Anti-IDH1 Monoclonal Antibody (9A285) can be used in WB,IF,FCM. |
| 别名 | PICD, IDPC, IDP, IDH, IDCD, HEL-S-26, HEL-216 |
| Ig Type | IgG1 |
| 克隆号 | 9A285 |
| 反应种属 | Human,Mouse,Monkey |
| 应用 | WBIFFCM |
| 推荐剂量 | WB: 1/500-1/2000; IF: 1/50-1/250; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human IDH1 (AA: 156-298) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | IDH1 |
| 基因ID | |
| 蛋白名称 | Isocitrate dehydrogenase [NADP] cytoplasmic |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |