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Anti-Phospho-MEK1/2 (Ser218, Ser222) Antibody (7E636)
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产品编号 TMAB-01451
Anti-Phospho-MEK1/2 (Ser218, Ser222) Antibody (7E636) 是一种 Rabbit 抗体，靶向 Phospho-MEK1/2 (Ser218, Ser222)。Anti-Phospho-MEK1/2 (Ser218, Ser222) Antibody (7E636) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
Anti-Phospho-MEK1/2 (Ser218, Ser222) Antibody (7E636)
Anti-Phospho-MEK1/2 (Ser218, Ser222) Antibody (7E636)
还可以产品编号 TMAB-01451
Anti-Phospho-MEK1/2 (Ser218, Ser222) Antibody (7E636) 是一种 Rabbit 抗体，靶向 Phospho-MEK1/2 (Ser218, Ser222)。Anti-Phospho-MEK1/2 (Ser218, Ser222) Antibody (7E636) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-Phospho-MEK1/2 (Ser218, Ser222) Antibody (7E636) is a Rabbit antibody targeting Phospho-MEK1/2 (Ser218, Ser222). Anti-Phospho-MEK1/2 (Ser218, Ser222) Antibody (7E636) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| 克隆号 | 7E636 |
| 交叉反应 | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Rabbit) |
| 验证活性 | Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Lane 3: Human Du145 cell lysates Lane 4: Human HepG2 cell lysates Lane 5: Human U251 cell lysates Lane 6: Human A549 cell cell lysates Primary: Anti-Phospho-MEK1/2 (Ser218 + Ser222) (TMAB-01451) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kDa Observed band size: 45 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole body. Cytoplasm. Nucleus. Note=Localizes at centrosomes during prometaphase, midzone during anaphase and midbody during telophase/cytokinesis. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008]. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human MEK1 around the phosphorylation site of Ser218/222 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | MAPK pathway,MAPK Pathway,Tyrosine Kinases |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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