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Anti-CD27/TNFRSF7 Antibody (7N314) 是一种 Rabbit 抗体,靶向 CD27/TNFRSF7。Anti-CD27/TNFRSF7 Antibody (7N314) 可用于 WB,ELISA。
Anti-CD27/TNFRSF7 Antibody (7N314) 是一种 Rabbit 抗体,靶向 CD27/TNFRSF7。Anti-CD27/TNFRSF7 Antibody (7N314) 可用于 WB,ELISA。
产品描述 | Anti-CD27/TNFRSF7 Antibody (7N314) is a Rabbit antibody targeting CD27/TNFRSF7. Anti-CD27/TNFRSF7 Antibody (7N314) can be used in WB,ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 7N314 |
交叉反应 | Human |
验证活性 | Anti-CD27 rabbit monoclonal antibody at 1:500 dilution. -Lane A: Raji Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:29 kDa. -Observed band size:65 kDa |
应用 | WB,ELISA |
推荐剂量 | WB: 1:500-1:2000; ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD27/TNFRSF7 (rh CD27/TNFRSF7; TMPY-03401; P26842; Met1-Ile192). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
偶联 | Unconjugated |
免疫原 | Recombinant Human CD27/TNFRSF7 Protein (TMPY-03401) |
抗原种属 | Human |
研究领域 | Cancer Drug Targets |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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