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Anti-RUNX2 Antibody (4W937)

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Anti-RUNX2 Antibody (4W937)
产品编号 TMAC-03664
别名 SL3/AKV core binding factor alpha A subunit, SL3 3 enhancer factor 1 alpha A subunit, RUNX 2, Runt-related Transcription Factor 2, Runt related transcription factor 2, Runt domain, Polyomavirus enhancer binding protein 2 alpha A subunit, PEBP2-alpha A, PEBP2aA1, PEBP2A2, PEBP2A1, PEBP2 alpha A, PEA2aA, PEA2 alpha A, OTTHUMP00000016533, Osteoblast specific transcription factor 2, OSF2, OSF 2, Oncogene AML 3, MGC120023, Core binding factor subunit alpha 1, Core binding factor runt domain alpha subunit 1, Core binding factor, Cleidocranial dysplasia 1, CLCD, CCD1, CCD, CBFA1, CBF alpha 1, AML3

Anti-RUNX2 Antibody (4W937) 是一种 Rabbit 抗体，靶向 RUNX2。Anti-RUNX2 Antibody (4W937) 可用于 ICC/IF,IHC,WB。

Anti-RUNX2 Antibody (4W937)

Anti-RUNX2 Antibody (4W937)

Rating icon 还可以
Anti-RUNX2 Antibody (4W937)
产品编号 TMAC-03664 别名 SL3/AKV core binding factor alpha A subunit, SL3 3 enhancer factor 1 alpha A subunit, RUNX 2, Runt-related Transcription Factor 2, Runt related transcription factor 2, Runt domain, Polyomavirus enhancer binding protein 2 alpha A subunit, PEBP2-alpha A, PEBP2aA1, PEBP2A2, PEBP2A1, PEBP2 alpha A, PEA2aA, PEA2 alpha A, OTTHUMP00000016533, Osteoblast specific transcription factor 2, OSF2, OSF 2, Oncogene AML 3, MGC120023, Core binding factor subunit alpha 1, Core binding factor runt domain alpha subunit 1, Core binding factor, Cleidocranial dysplasia 1, CLCD, CCD1, CCD, CBFA1, CBF alpha 1, AML3

Anti-RUNX2 Antibody (4W937) 是一种 Rabbit 抗体，靶向 RUNX2。Anti-RUNX2 Antibody (4W937) 可用于 ICC/IF,IHC,WB。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-RUNX2 Antibody (4W937) is a Rabbit antibody targeting RUNX2. Anti-RUNX2 Antibody (4W937) can be used in ICC/IF,IHC,WB.
别名SL3/AKV core binding factor alpha A subunit, SL3 3 enhancer factor 1 alpha A subunit, RUNX 2, Runt-related Transcription Factor 2, Runt related transcription factor 2, Runt domain, Polyomavirus enhancer binding protein 2 alpha A subunit, PEBP2-alpha A, PEBP2aA1, PEBP2A2, PEBP2A1, PEBP2 alpha A, PEA2aA, PEA2 alpha A, OTTHUMP00000016533, Osteoblast specific transcription factor 2, OSF2, OSF 2, Oncogene AML 3, MGC120023, Core binding factor subunit alpha 1, Core binding factor runt domain alpha subunit 1, Core binding factor, Cleidocranial dysplasia 1, CLCD, CCD1, CCD, CBFA1, CBF alpha 1, AML3
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-RUNX2 antibody. Counter stained with hematoxylin.
2. ICC staining RUNX2 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
ICC/IF
IHC
WB
推荐剂量
WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The mammalian Runt-related transcription factor (RUNX) family comprises three members, RUNX1 (also designated AML-1, PEBP2αB, CBFA2), RUNX2 (also designated AML-3, PEBP2αA, CBFA1, Osf2) and RUNX3 (also designated AML-2, PEBPαC, CBFA3). RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX2 is essential for skeletal mineralization in that it stimulates osteoblast differentiation of mesenchymal stem cells, promotes chondrocyte hypertrophy and contributes to endothelial cell migration and vascular invasion of developing bones. Regulating RUNX2 expression may be a useful therapeutic tool for promoting bone formation. Mutations in the C-terminus of RUNX2 are associated with cleidocranial dysplasia syndrome, an autosomal-dominant skeletal dysplasia syndrome that is characterized by widely patent calvarial sutures, clavicular hypoplasia, supernumerary teeth, and short stature.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q13950
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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