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ATG14 Protein, Human, Recombinant (His & Myc)

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货号 TMPH-01003

别名 KIAA0831, Beclin 1-associated autophagy-related key regulator, Barkor, Autophagy-related protein 14-like protein (Atg14L), ATG14L, ATG14

ATG14 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 60.3 kDa and the accession number is Q6ZNE5.

ATG14 Protein, Human, Recombinant (His & Myc)
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ATG14 Protein, Human, Recombinant (His & Myc)

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货号 TMPH-01003 别名 KIAA0831, Beclin 1-associated autophagy-related key regulator, Barkor, Autophagy-related protein 14-like protein (Atg14L), ATG14L, ATG14

ATG14 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 60.3 kDa and the accession number is Q6ZNE5.

规格价格库存数量
5 μg
¥ 489
20日内发货
10 μg
¥ 797
20日内发货
20 μg
¥ 1,320
20日内发货
50 μg
¥ 1,970
20日内发货
100 μg
¥ 2,680
20日内发货
200 μg
¥ 4,160
20日内发货
500 μg
¥ 7,490
20日内发货
1 mg
¥ 11,700
20日内发货
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产品介绍

生物活性
产品描述
ATG14 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 60.3 kDa and the accession number is Q6ZNE5.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1. Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK. Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion. Modulates the hepatic lipid metabolism.
种属
Human
表达系统
E. coli
标签N-10xHis, C-Myc
蛋白编号Q6ZNE5
氨基酸序列MASPSGKGARALEAPGCGPRPLARDLVDSVDDAEGLYVAVERCPLCNTTRRRLTCAKCVQSGDFVYFDGRDRERFIDKKERLSRLKSKQEEFQKEVLKAMEGKWITDQLRWKIMSCKMRIEQLKQTICKGNEEMEKNSEGLLKTKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTIDLRSHYERLANLRRSHILELTSVIFPIEEVKTGVRDPADVSSESDSAMTSSTVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYSWVEEKKTTQGPDMEQSNPAYTISAALCYATQLVNILSHILDVNLPKKLCNSEFCGENLSKQKFTRAVKKLNANILYLCFSQHVNLDQLQPLHTLRNLMYLVSPSSEHLGRSGPFEVRADLEESMEFVDPGVAGESDESGDERVSDEETDLGTDWENLPSPRFCDIPSQSVEVSQSQSTQASPPIASSSAGGMISSAAASVTSWFKAYTGHR
蛋白构建1-492 aa
蛋白纯度
> 90% as determined by SDS-PAGE.
缓冲液Tris-based buffer, 50% glycerol
复溶方法A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名KIAA0831, Beclin 1-associated autophagy-related key regulator, Barkor, Autophagy-related protein 14-like protein (Atg14L), ATG14L, ATG14
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量60.3 kDa (predicted)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

KIAA 0831Atg14LAtg 14LATG 14
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