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Anti-LRRK2 Polyclonal Antibody

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货号 TMAB-08424

Anti-LRRK2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LRRK2。Anti-LRRK2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-LRRK2 Polyclonal Antibody

Anti-LRRK2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08424

Anti-LRRK2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LRRK2。Anti-LRRK2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-LRRK2 Polyclonal Antibody is a Rabbit antibody targeting LRRK2. Anti-LRRK2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Cow)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane. Mitochondrion. Localized in the cytoplasm and associated with cellular membrane structures. Associates with the mitochondrial outer membrane.
组织特异性Expressed throughout the adult brain, but at a lower level than in heart and liver. Also expressed in placenta, lung, skeletal muscle, kidney and pancreas. In the brain, expressed in the cerebellum, cerebral cortex, medulla, spinal cord occipital pole, frontal lobe, temporal lobe and putamen. Expression is particularly high in brain dopaminoceptive areas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景LRRK2 (Dardarin) is encoded by the gene LRRK2. Genetic mutations of LRRK2 have been linked to Parkinsonism and synucleinopathies. LRRK2 belongs to the ROCO protein family and includes a protein kinase domain of the MAPKKK class and several other major functional domains.
抗原信息
免疫原
KLH conjugated synthetic peptide: human LRRK2
抗原种属
Human
基因名称
LRRK2
基因ID
蛋白名称
Leucine-rich repeat serine/threonine-protein kinase 2
Uniprot ID
功能
May play a role in the phosphorylation of proteins central to Parkinson disease. Phosphorylates PRDX3. May also have GTPase activity.
化学信息
分子量Theoretical: 286 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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