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Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated

Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated

产品编号 TMPY-05813
别名: HGL, NRG1-IT2, MST131, NDF, SMDF, neuregulin 1, HRG, GGF, GGF2, MSTP131, HRG1, ARIA, HRGA

Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297.

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Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated
规格 价格/CNY 货期 数量
20 μg ¥ 1,950 5日内发货
100 μg ¥ 4,620 5日内发货
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产品目录号及名称: Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated (TMPY-05813)
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生物活性 Testing in progress
产品描述 Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297.
种属 Human
表达系统 HEK293 Cells
标签 Tag Free
蛋白编号 Q02297
别名 HGL, NRG1-IT2, MST131, NDF, SMDF, neuregulin 1, HRG, GGF, GGF2, MSTP131, HRG1, ARIA, HRGA
蛋白构建 The N-terminal fragment (Ser2-Lys246) of Human NRG1 isoform beta1 (Q02297-6) was expressed. The purified protein was biotinylated in vitro.
蛋白纯度 > 75 % as determined by SDS-PAGE.
分子量 26.8 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and alternative splicing of a single gene. Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. NRG1 is a schizophrenia candidate gene and plays an important role in brain development and neural function. Schizophrenia is a complex disorder, with etiology likely due to epistasis.

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Keywords

Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated GGF-2 MSTP 131 HGL NRG1-IT2 MST131 GGF 2 NDF SMDF neuregulin 1 HRG-1 HRG GGF MST 131 GGF2 MSTP131 MST-131 HRG 1 HRG1 MSTP-131 ARIA HRGA recombinant recombinant-proteins proteins protein

 

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