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顶部生物活性储存和溶解信息计算器

Anti-Aminoacylase 1 Antibody (1K198)

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产品编号 TMAY-00964

别名 HEL-S-5, aminoacylase 1, ACY1D, ACY-1

Anti-Aminoacylase 1 Antibody (1K198) 是一种 Rabbit 抗体，靶向 Aminoacylase 1。Anti-Aminoacylase 1 Antibody (1K198) 可用于 IHC-P。

Anti-Aminoacylase 1 Antibody (1K198)

Anti-Aminoacylase 1 Antibody (1K198)

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产品编号 TMAY-00964 别名 HEL-S-5, aminoacylase 1, ACY1D, ACY-1

Anti-Aminoacylase 1 Antibody (1K198) 是一种 Rabbit 抗体，靶向 Aminoacylase 1。Anti-Aminoacylase 1 Antibody (1K198) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-Aminoacylase 1 Antibody (1K198) is a Rabbit antibody targeting Aminoacylase 1. Anti-Aminoacylase 1 Antibody (1K198) can be used in IHC-P.
别名HEL-S-5, aminoacylase 1, ACY1D, ACY-1
Ig Type
Rabbit IgG
克隆号
1K198
交叉反应
Human
特异性
Human Aminoacylase 1
验证活性
Immunochemical staining of human ACY1 in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to nephric tubule.
应用IHC-P
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ACY1 / Aminoacylase-1 (rh ACY1 / Aminoacylase-1; TMPY-01058; NP_000657.1; Met1-Ser408).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Aminoacylase 1 (ACY1), a metalloenzyme that removes amide-linked ACY1 groups from amino acids and may play a role in regulating responses to oxidative stress. Both the C-terminal fragment found in the two-hybrid screen and full-length ACY1 co-immunoprecipitate with SphK1. Though both C-terminal and full-length proteins slightly reduce SphK1 activity measured in vitro, the C-terminal fragment inhibits while full-length ACY1 potentiates the effects of SphK1 on proliferation and apoptosis. It suggested that ACY1 physically interacts with SphK1 and may influence its physiological functions. As a homodimeric zinc-binding enzyme, Aminoacylase 1 catalyzes the hydrolysis of N alpha-acylated amino acids. Deficiency of Aminoacylase 1 due to mutations in the Aminoacylase 1 (ACY1) gene follows an autosomal-recessive trait of inheritance and is characterized by accumulation of N-acetyl amino acids in the urine.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human ACY1 / Aminoacylase-1 protein (TMPY-01058)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

ACY1ACY 1

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