细胞重编程化合物库

细胞重编程化合物库

Reprogramming Compound Library

很棒

货号 L8110

细胞重编程指的是已分化的体细胞在一定条件下被逆转恢复到多能或全能性状态的过程。传统的重编程技术存在整合外源基因等问题在临床应用中存在局限性，而小分子化合物诱导多能干细胞的研究开辟了一条全新的体细胞重编程方法。小分子化合物诱导重编程的优点包括：不整合到基因组，无免疫原性；可以透过细胞膜直接作用于靶点，操作方便；效应可逆，可同时调控多个靶点，精确调控细胞命运。小分子化合物诱导的多能干细胞在药物发现、细胞治疗、疾病建模中具有很大的潜力，为治疗重大疾病开辟了新的途径。

TargetMol 细胞重编程化合物库是2240 种细胞重编程相关信号通路的生物活性小分子化合物的特有集合，为细胞重编程研究提供有效工具

TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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Apoptosis

Autophagy

PI3K

VEGFR

Ras

EGFR

p38 MAPK

HDAC

mTOR

ERK

JAK

Akt

Wnt/beta-catenin

STAT

NF-κB

PDGFR

Epigenetic Reader Domain

AMPK

Histone Methyltransferase

GSK-3

Endogenous Metabolite

Raf

FGFR

Src

CDK

TGF-beta/Smad

ROS

Antibacterial

JNK

c-Met/HGFR

FLT

MAPK

c-Kit

PKC

MEK

ROCK

DNA/RNA Synthesis

Reactive Oxygen Species

HIF/HIF Prolyl-Hydroxylase

Kras

Parasite

Nucleoside Antimetabolite/Analog

DNA-PK

Tyrosine Kinases

Caspase

Bcr-Abl

S6 Kinase

Hedgehog/Smoothened

Monoamine Oxidase

TNF

ATM/ATR

Mitochondrial Metabolism

COX

ALK

PKA

Virus Protease

Bcl-2 Family

HIV Protease

c-RET

HIF

Antibiotic

Calcium Channel

Interleukin

Influenza Virus

Dehydrogenase

Aurora Kinase

NO Synthase

Casein Kinase

PDK

c-Myc

MAO

PARP

PERK

Mitophagy

Potassium Channel

TLR

IGF-1R

HER

Cytochromes P450

Histone Acetyltransferase

HSV

Sirtuin

Ferroptosis

PPAR

Gamma-secretase

Rho

Antifungal

c-Fms

Phosphatase

Retinoid Receptor

Pim

Smo

MMP

PI4K

Nrf2

Beta Amyloid

TAM Receptor

IL Receptor

AXL

FAK

PDE

MLK

DNA Methyltransferase

IκB/IKK

Microtubule Associated

BTK

Sodium Channel

AChR

MNK

Syk

Drug Metabolite

PTEN

MDM-2/p53

Trk receptor

HCV Protease

PROTACs

Adrenergic Receptor

Tie-2

SARS-CoV

Chk

Serine/threonin kinase

Tyrosinase

Antioxidant

Histone Demethylase

IFNAR

CaMK

Adenosine Receptor

SIK

HSP

Antifection

Topoisomerase

p53

DYRK

MELK

CSF-1R

Serine Protease

PLK

Estrogen/progestogen Receptor

ASK

LDL

OXPHOS

Cannabinoid Receptor

ATPase

HBV

Transferase

TRP/TRPV Channel

Antiviral

5-HT Receptor

SGK

Ephrin Receptor

Reverse Transcriptase

GABA Receptor

Histamine Receptor

TOPK

Glucosidase

PYK2

RIP kinase

Proton pump

P-gp

Prostaglandin Receptor

Carbonic Anhydrase

Porcupine

Anti-infection

NOD-like Receptor (NLR)

Lipoxygenase

ROS Kinase

PD-1/PD-L1

Integrin

Estrogen Receptor/ERR

Dopamine Receptor

Survivin

Discoidin Domain Receptor (DDR)

MyD88

Aryl Hydrocarbon Receptor

FKBP

Cholinesterase (ChE)

glycosidase

ATP Citrate Lyase

Hippo pathway

NADPH

Hck

Lipid

transporter

GTPase

IRAK

DNA Alkylation

KLF

Adenylate cyclase

UGT

Fatty Acid Synthase

Methionine Adenosyltransferase (MAT)

Kinesin

Chloride channel

NOS

RAR/RXR

Glutathione Peroxidase

FXR

IRE1

Guanylate cyclase

Opioid Receptor

Cadherin

LRRK2

Pyroptosis

NADPH-oxidase

E1/E2/E3 Enzyme

FAAH

CCR

GluR

DNA

BACE

Necroptosis

GRK

GPCR

PAK

cAMP

PAI-1

NOD

RAAS

Cholecystokinin Receptor

Myosin

Beta-Secretase

Acyltransferase

Phospholipase

ROR

Ligands for Target Protein for PROTAC

Immunology/Inflammation related

DUB

PGK1

MRP

Antifolate

Glutaminase

Thrombopoietin Receptor

Androgen Receptor

Indoleamine 2,3-Dioxygenase (IDO)

BCRP

PGE Synthase

Aminopeptidase

DAPK

Protease-activated Receptor

p97

Monocarboxylate transporter

Prolyl Endopeptidase (PREP)

MAGL

CXCR

STING

GPX

RXFP receptor

NR4A

IAP

iGluR

ABC Transporter

Monoamine Transporter

CRISPR/Cas9

Hydroxylase

CFTR

Imidazoline Receptor

YAP

OCT

RANKL/RANK

IDO

Glucocorticoid Receptor

Na-K-Cl cotransporter

Molecular Glues

ACK1

SGLT

hCE

BMI-1

AhR

Mdm2

Y Box Binding Protein 1

Arginase

Na+/Ca2+ Exchanger

gp120/CD4

Carboxypeptidase

Aromatase

Gap Junction Protein

NPC1L1

DHFR

Reductase

AAK1

Decarboxylase

Apelin receptor

Dynamin

Amino Acids and Derivatives

Lipase

NMDAR

Hexokinase

Angiotensin-converting Enzyme (ACE)

PANoptosis

S1P Receptor

ADC Cytotoxin

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