细胞重编程化合物库

细胞重编程化合物库

Reprogramming Compound Library

很棒

产品编号 L8110

细胞重编程指的是已分化的体细胞在一定条件下被逆转恢复到多能或全能性状态的过程。传统的重编程技术存在整合外源基因等问题在临床应用中存在局限性，而小分子化合物诱导多能干细胞的研究开辟了一条全新的体细胞重编程方法。小分子化合物诱导重编程的优点包括：不整合到基因组，无免疫原性；可以透过细胞膜直接作用于靶点，操作方便；效应可逆，可同时调控多个靶点，精确调控细胞命运。小分子化合物诱导的多能干细胞在药物发现、细胞治疗、疾病建模中具有很大的潜力，为治疗重大疾病开辟了新的途径。

TargetMol 细胞重编程化合物库是2240 种细胞重编程相关信号通路的生物活性小分子化合物的特有集合，为细胞重编程研究提供有效工具

TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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Autophagy

PI3K

VEGFR

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EGFR

HDAC

p38 MAPK

mTOR

JAK

ERK

Akt

Wnt/beta-catenin

STAT

PDGFR

Epigenetic Reader Domain

Histone Methyltransferase

AMPK

Endogenous Metabolite

GSK-3

NF-κB

Raf

FGFR

CDK

Src

TGF-beta/Smad

c-Kit

FLT

c-Met/HGFR

Antibacterial

MAPK

JNK

PKC

MEK

ROCK

Reactive Oxygen Species

HIF/HIF Prolyl-Hydroxylase

Kras

DNA/RNA Synthesis

Nucleoside Antimetabolite/Analog

Parasite

DNA-PK

Tyrosine Kinases

S6 Kinase

Hedgehog/Smoothened

Monoamine Oxidase

ALK

Mitochondrial Metabolism

ATM/ATR

Bcr-Abl

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c-RET

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HIF

PDK

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TLR

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HER

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IGF-1R

PPAR

Smo

Rho

HSV

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Retinoid Receptor

Phosphatase

MMP

Interleukin

Antifungal

NO Synthase

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IL Receptor

DNA Methyltransferase

FAK

IκB/IKK

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MNK

PDE

HCV Protease

Syk

PTEN

Sodium Channel

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ROS

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Drug Metabolite

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p53

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LDL

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ASK

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Reverse Transcriptase

Glucosidase

OXPHOS

Adenosine Receptor

Prostaglandin Receptor

Porcupine

Anti-infection

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PYK2

ROS Kinase

transporter

Lipoxygenase

Estrogen/progestogen Receptor

Carbonic Anhydrase

SGK

BTK

MyD88

FKBP

IRAK

ATP Citrate Lyase

Cholinesterase (ChE)

Integrin

GTPase

FXR

Dopamine Receptor

RIP kinase

Hippo pathway

Discoidin Domain Receptor (DDR)

NADPH

KLF

Lipid

Aryl Hydrocarbon Receptor

Myosin

PD-1/PD-L1

P-gp

Estrogen Receptor/ERR

IRE1

DUB

NADPH-oxidase

NOS

RAR/RXR

ROR

Cholecystokinin Receptor

Guanylate cyclase

GluR

Phospholipase

NOD-like Receptor (NLR)

Methionine Adenosyltransferase (MAT)

FAAH

DNA

GPCR

Survivin

GRK

RAAS

Beta-Secretase

NOD

cAMP

CCR

UGT

BACE

Glutathione Peroxidase

Adenylyl Cyclase

Chloride channel

Opioid Receptor

PAI-1

DNA Alkylation

Angiotensin-converting Enzyme (ACE)

Hck

PAK

PGK1

Glucocorticoid Receptor

Lipase

YAP

Pyroptosis

MRP

BCRP

Hexokinase

IAP

CXCR

Mdm2

MAGL

S1P Receptor

Decarboxylase

Aromatase

CRISPR/Cas9

ACK1

IDO

Indoleamine 2,3-Dioxygenase (IDO)

Imidazoline Receptor

CFTR

Immunology/Inflammation related

iGluR

Protease-activated Receptor

Y Box Binding Protein 1

Prolyl Endopeptidase (PREP)

Ligands for Target Protein for PROTAC

OCT

RXFP receptor

BMI-1

AAK1

DHFR

DAPK

SGLT

Aminopeptidase

NPC1L1

Amino Acids and Derivatives

Androgen Receptor

Molecular Glues

Apelin receptor

Dynamin

E1/E2/E3 Enzyme

Arginase

Carboxypeptidase

Cadherin

Necroptosis

gp120/CD4

Thrombopoietin Receptor

NR4A

Kinesin

Na-K-Cl cotransporter

NMDAR

AhR

hCE

GPX

PGE Synthase

Gap Junction Protein

Na+/Ca2+ Exchanger

Acyltransferase

p97

Fatty Acid Synthase

Antifolate

STING

Hydroxylase

LRRK2

ABC Transporter

ADC Cytotoxin

产品编号 L8110

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