细胞重编程化合物库

细胞重编程化合物库

Reprogramming Compound Library

很棒

货号 L8110

细胞重编程指的是已分化的体细胞在一定条件下被逆转恢复到多能或全能性状态的过程。传统的重编程技术存在整合外源基因等问题在临床应用中存在局限性，而小分子化合物诱导多能干细胞的研究开辟了一条全新的体细胞重编程方法。小分子化合物诱导重编程的优点包括：不整合到基因组，无免疫原性；可以透过细胞膜直接作用于靶点，操作方便；效应可逆，可同时调控多个靶点，精确调控细胞命运。小分子化合物诱导的多能干细胞在药物发现、细胞治疗、疾病建模中具有很大的潜力，为治疗重大疾病开辟了新的途径。

TargetMol 细胞重编程化合物库是2240 种细胞重编程相关信号通路的生物活性小分子化合物的特有集合，为细胞重编程研究提供有效工具

TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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Apoptosis

Autophagy

PI3K

VEGFR

Ras

EGFR

p38 MAPK

HDAC

mTOR

ERK

Akt

JAK

Wnt/beta-catenin

STAT

NF-κB

PDGFR

Epigenetic Reader Domain

AMPK

Histone Methyltransferase

GSK-3

Endogenous Metabolite

Raf

FGFR

CDK

Src

TGF-beta/Smad

ROS

Antibacterial

JNK

c-Met/HGFR

FLT

c-Kit

MAPK

PKC

MEK

ROCK

DNA/RNA Synthesis

Reactive Oxygen Species

HIF/HIF Prolyl-Hydroxylase

Kras

Parasite

Nucleoside Antimetabolite/Analog

DNA-PK

Caspase

Tyrosine Kinases

Hedgehog/Smoothened

S6 Kinase

Bcr-Abl

TNF

Monoamine Oxidase

ATM/ATR

Mitochondrial Metabolism

ALK

COX

PKA

Virus Protease

Bcl-2 Family

c-RET

HIV Protease

HIF

Calcium Channel

Antibiotic

Dehydrogenase

PDK

Influenza Virus

Interleukin

PERK

c-Myc

MAO

NO Synthase

Aurora Kinase

Casein Kinase

PARP

Mitophagy

Cytochromes P450

TLR

Potassium Channel

IGF-1R

HER

Histone Acetyltransferase

PPAR

Gamma-secretase

HSV

Sirtuin

Ferroptosis

Smo

Antifungal

c-Fms

PI4K

MMP

Rho

Pim

Phosphatase

Retinoid Receptor

TAM Receptor

Beta Amyloid

FAK

IL Receptor

Nrf2

IκB/IKK

DNA Methyltransferase

PDE

AChR

Microtubule Associated

MNK

Sodium Channel

MLK

SARS-CoV

Drug Metabolite

Syk

MDM-2/p53

PTEN

Tie-2

Chk

Trk receptor

Antioxidant

Adrenergic Receptor

HCV Protease

SIK

HSP

PROTACs

Histone Demethylase

Adenosine Receptor

IFNAR

CaMK

Serine/threonin kinase

p53

CSF-1R

Antifection

Serine Protease

PLK

ATPase

DYRK

MELK

Topoisomerase

Tyrosinase

Histamine Receptor

TOPK

Glucosidase

ASK

HBV

Ephrin Receptor

Reverse Transcriptase

GABA Receptor

Transferase

TRP/TRPV Channel

Antiviral

5-HT Receptor

OXPHOS

Cannabinoid Receptor

Integrin

Estrogen/progestogen Receptor

PYK2

RIP kinase

Survivin

Carbonic Anhydrase

Porcupine

Lipoxygenase

ROS Kinase

PD-1/PD-L1

SGK

Anti-infection

NOD-like Receptor (NLR)

Proton pump

LDL

P-gp

BTK

Estrogen Receptor/ERR

Myosin

Dopamine Receptor

Discoidin Domain Receptor (DDR)

KLF

Cholinesterase (ChE)

glycosidase

ATP Citrate Lyase

Hippo pathway

GTPase

IRAK

NADPH

Hck

Lipid

transporter

NOS

MyD88

FXR

Aryl Hydrocarbon Receptor

Prostaglandin Receptor

FKBP

RAAS

Cholecystokinin Receptor

DNA Alkylation

Beta-Secretase

Phospholipase

Adenylyl Cyclase

UGT

Fatty Acid Synthase

Methionine Adenosyltransferase (MAT)

Kinesin

ROR

Immunology/Inflammation related

Angiotensin-converting Enzyme (ACE)

DUB

IAP

E1/E2/E3 Enzyme

FAAH

CCR

GluR

DNA

GPCR

PAK

cAMP

PAI-1

NOD

BACE

Necroptosis

GRK

Chloride channel

RAR/RXR

Glutathione Peroxidase

IRE1

Guanylate cyclase

Opioid Receptor

Cadherin

Pyroptosis

NADPH-oxidase

PGK1

NPC1L1

DHFR

Reductase

AAK1

Acyltransferase

Decarboxylase

MRP

Antifolate

Thrombopoietin Receptor

Indoleamine 2,3-Dioxygenase (IDO)

Androgen Receptor

BCRP

PGE Synthase

Aminopeptidase

DAPK

Protease-activated Receptor

p97

Apelin receptor

Dynamin

Amino Acids and Derivatives

Ligands for Target Protein for PROTAC

Lipase

NMDAR

Hexokinase

S1P Receptor

NR4A

iGluR

ABC Transporter

Monoamine Transporter

Hydroxylase

CFTR

Imidazoline Receptor

Mdm2

Y Box Binding Protein 1

Arginase

Na+/Ca2+ Exchanger

gp120/CD4

Carboxypeptidase

Aromatase

Gap Junction Protein

YAP

OCT

RANKL/RANK

IDO

Glucocorticoid Receptor

Na-K-Cl cotransporter

Molecular Glues

ACK1

SGLT

hCE

BMI-1

AhR

Monocarboxylate transporter

Prolyl Endopeptidase (PREP)

MAGL

CXCR

STING

LRRK2

GPX

RXFP receptor

ADC Cytotoxin

货号 L8110

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