细胞重编程化合物库

细胞重编程化合物库

Reprogramming Compound Library

很棒

货号 L8110

细胞重编程指的是已分化的体细胞在一定条件下被逆转恢复到多能或全能性状态的过程。传统的重编程技术存在整合外源基因等问题在临床应用中存在局限性，而小分子化合物诱导多能干细胞的研究开辟了一条全新的体细胞重编程方法。小分子化合物诱导重编程的优点包括：不整合到基因组，无免疫原性；可以透过细胞膜直接作用于靶点，操作方便；效应可逆，可同时调控多个靶点，精确调控细胞命运。小分子化合物诱导的多能干细胞在药物发现、细胞治疗、疾病建模中具有很大的潜力，为治疗重大疾病开辟了新的途径。

TargetMol 细胞重编程化合物库是2240 种细胞重编程相关信号通路的生物活性小分子化合物的特有集合，为细胞重编程研究提供有效工具

TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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Apoptosis

Autophagy

PI3K

VEGFR

Ras

EGFR

p38 MAPK

HDAC

ERK

mTOR

Akt

JAK

Wnt/beta-catenin

STAT

NF-κB

PDGFR

Epigenetic Reader Domain

Histone Methyltransferase

AMPK

GSK-3

Endogenous Metabolite

Raf

FGFR

Src

CDK

TGF-beta/Smad

ROS

Antibacterial

JNK

c-Met/HGFR

MAPK

FLT

c-Kit

PKC

MEK

DNA/RNA Synthesis

ROCK

Reactive Oxygen Species

HIF/HIF Prolyl-Hydroxylase

Kras

Parasite

Nucleoside Antimetabolite/Analog

DNA-PK

Caspase

Tyrosine Kinases

Hedgehog/Smoothened

S6 Kinase

Bcr-Abl

TNF

Monoamine Oxidase

Mitochondrial Metabolism

ALK

ATM/ATR

COX

PKA

Virus Protease

Bcl-2 Family

c-RET

HIV Protease

HIF

Dehydrogenase

Calcium Channel

PDK

Antibiotic

Influenza Virus

c-Myc

MAO

Interleukin

NO Synthase

PARP

Aurora Kinase

Casein Kinase

PERK

Mitophagy

Cytochromes P450

TLR

IGF-1R

Histone Acetyltransferase

Potassium Channel

HER

Ferroptosis

PPAR

Gamma-secretase

HSV

Sirtuin

Antifungal

Smo

c-Fms

PI4K

Phosphatase

Pim

Rho

MMP

Retinoid Receptor

Beta Amyloid

TAM Receptor

IL Receptor

Nrf2

FAK

PDE

IκB/IKK

DNA Methyltransferase

MNK

AChR

Sodium Channel

Microtubule Associated

MLK

Drug Metabolite

PTEN

SARS-CoV

MDM-2/p53

Syk

HCV Protease

Antioxidant

Tie-2

Adrenergic Receptor

Chk

Trk receptor

PROTACs

Adenosine Receptor

IFNAR

Histone Demethylase

Serine/threonin kinase

SIK

CaMK

HSP

Tyrosinase

p53

DYRK

Serine Protease

CSF-1R

Topoisomerase

Antifection

MELK

PLK

ATPase

Transferase

Histamine Receptor

TOPK

HBV

TRP/TRPV Channel

Glucosidase

OXPHOS

Antiviral

Ephrin Receptor

ASK

Reverse Transcriptase

5-HT Receptor

GABA Receptor

Cannabinoid Receptor

Proton pump

Carbonic Anhydrase

Integrin

Estrogen/progestogen Receptor

PYK2

RIP kinase

LDL

Lipoxygenase

Survivin

P-gp

Porcupine

SGK

Anti-infection

ROS Kinase

NOD-like Receptor (NLR)

PD-1/PD-L1

BTK

NOS

Dopamine Receptor

MyD88

NADPH

GTPase

Estrogen Receptor/ERR

Hck

FXR

Aryl Hydrocarbon Receptor

Cholinesterase (ChE)

glycosidase

ATP Citrate Lyase

Lipid

Prostaglandin Receptor

transporter

Hippo pathway

FKBP

KLF

Discoidin Domain Receptor (DDR)

IRAK

GPCR

Chloride channel

Adenylyl Cyclase

RAR/RXR

ROR

BACE

RAAS

Necroptosis

Glutathione Peroxidase

Cholecystokinin Receptor

Immunology/Inflammation related

IAP

Myosin

IRE1

E1/E2/E3 Enzyme

UGT

GRK

Guanylate cyclase

Opioid Receptor

Fatty Acid Synthase

DNA Alkylation

PAK

FAAH

CCR

Angiotensin-converting Enzyme (ACE)

Cadherin

cAMP

GluR

DNA

DUB

Beta-Secretase

Acyltransferase

PAI-1

Pyroptosis

Methionine Adenosyltransferase (MAT)

Phospholipase

NADPH-oxidase

NOD

Kinesin

PGK1

Apelin receptor

Mdm2

Monocarboxylate transporter

NPC1L1

DHFR

Dynamin

Amino Acids and Derivatives

Y Box Binding Protein 1

Ligands for Target Protein for PROTAC

Arginase

YAP

Reductase

Na+/Ca2+ Exchanger

Lipase

gp120/CD4

OCT

MRP

AAK1

Antifolate

Glutaminase

NR4A

RANKL/RANK

IDO

Glucocorticoid Receptor

iGluR

Prolyl Endopeptidase (PREP)

NMDAR

ABC Transporter

Na-K-Cl cotransporter

Hexokinase

Monoamine Transporter

Molecular Glues

MAGL

ACK1

CXCR

Thrombopoietin Receptor

Androgen Receptor

Indoleamine 2,3-Dioxygenase (IDO)

SGLT

BCRP

PGE Synthase

STING

LRRK2

Aminopeptidase

Decarboxylase

hCE

Carboxypeptidase

GPX

Aromatase

Hydroxylase

RXFP receptor

Gap Junction Protein

DAPK

BMI-1

Protease-activated Receptor

p97

AhR

CFTR

Imidazoline Receptor

S1P Receptor

ADC Cytotoxin

货号 L8110

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