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顶部生物活性储存和溶解信息计算器

Anti-HDAC4 Antibody (5T743)

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Anti-HDAC4 Antibody (5T743)
产品编号 TMAC-01778
别名 histone deacetylase 4, HDAC-A, HDACA, HDAC-4, HD4, HA6116, BDMR, AHO3

Anti-HDAC4 Antibody (5T743) 是一种 Rabbit 抗体，靶向 HDAC4。Anti-HDAC4 Antibody (5T743) 可用于 WB,ICC/IF。

Anti-HDAC4 Antibody (5T743)

Anti-HDAC4 Antibody (5T743)

Rating icon 还可以
Anti-HDAC4 Antibody (5T743)
产品编号 TMAC-01778 别名 histone deacetylase 4, HDAC-A, HDACA, HDAC-4, HD4, HA6116, BDMR, AHO3

Anti-HDAC4 Antibody (5T743) 是一种 Rabbit 抗体，靶向 HDAC4。Anti-HDAC4 Antibody (5T743) 可用于 WB,ICC/IF。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-HDAC4 Antibody (5T743) is a Rabbit antibody targeting HDAC4. Anti-HDAC4 Antibody (5T743) can be used in WB,ICC/IF.
别名histone deacetylase 4, HDAC-A, HDACA, HDAC-4, HD4, HA6116, BDMR, AHO3
Ig Type
IgG
克隆号
5T743
交叉反应
Human
验证活性
1. Western blot analysis of HDAC4 on different lysates using anti-HDAC4 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: HepG2.
2. ICC staining HDAC4 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining HDAC4 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining HDAC4 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
推荐剂量
WB: 1:1000-2000; ICC/IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, p300/CBP, PCAF (p300/CBPassociated factor), HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P56524
化学信息
分子量Theoretical: 120 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

HDAC4HDAC 4HD-4HD 4HA-6116HA 6116AHO-3AHO 3

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