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Anti-sFlt1 Polyclonal Antibody

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货号 TMAB-12710

Anti-sFlt1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 sFlt1。Anti-sFlt1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-sFlt1 Polyclonal Antibody

Anti-sFlt1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12710

Anti-sFlt1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 sFlt1。Anti-sFlt1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-sFlt1 Polyclonal Antibody is a Rabbit antibody targeting sFlt1. Anti-sFlt1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:400-800; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cell membrane; Single-pass type I membrane protein. Endosome. Note=Autophosphorylation promotes ubiquitination and endocytosis;Isoform 2: Secreted;Isoform 3: Secreted;Isoform 4: Secreted;Isoform 5: Cytoplasm (Potential);Isoform 6: Cytoplasm (Potential);Isoform 7: Cytoplasm (Potential).
组织特异性Detected in normal lung, but also in placenta,liver, kidney, heart and brain tissues. Specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. Isoform 2 is strongly expressed in placenta. Isoform 3 is expressed in corneal epithelial cells (at protein level). Isoform 3 is expressed in vascular smooth muscle cells (VSMC).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes.
抗原信息
免疫原
Recombinant Protein: human sFlt1 protein
抗原种属
Human
基因名称
FLT1
基因ID
蛋白名称
Vascular endothelial growth factor receptor 1
Uniprot ID
功能
Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
化学信息
分子量Theoretical: 77 kDa. Actual: 130 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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