GPRC5D Protein, Human, Recombinant, Biotinylated

Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells.

规格	价格/CNY		数量
20 μg	￥ 5,330	5日内发货
100 μg	￥ 10,600	5日内发货
500 μg	￥ 33,800	5日内发货

规格

价格/CNY

货期

数量

20 μg

￥ 5,330

5日内发货

100 μg

￥ 10,600

5日内发货

500 μg

￥ 33,800

5日内发货

生物活性

Immobilized Biotinylated Human GPRC5D-VLP (Full Length) Protein at 5 μg/mL (100 μL/well) on streptavidin precoated (2 μg/well) can bind Anti-Human GPRC5D Antibody, Human IgG1, the EC50 is 4-12ng/mL.

产品描述

种属	Human
表达系统	HEK293
标签	Tag Free
蛋白编号	Q9NZD1-1
别名	GPRC5D
蛋白构建	A DNA sequence encoding the human GPRC5D (Q9NZD1-1) (Met1-Val345) was expressed.
分子量	38.80 kDa (predicted)

内毒素	< 1.0 EU per μg of the protein as determined by the LAL method
缓冲液	Supplied as sterile solution in 50mM HEPES, 150mM NaCI, 10% Trehalose, pH 7.2. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA.
存储	Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
运输方式	It is supplied and shipped as Solution with dry ice.
研究背景	Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells.