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Anti-HSPA5 Antibody (2X960)
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产品编号 TMAC-01726
别名 Immunoglobulin heavy chain-binding protein, HSPA 5, HSP70 family protein 5, Heat shock protein family A member 5, Heat shock protein 70 family protein 5, GRP-78, GRP78, Endoplasmic reticulum chaperone BiP, EC 3.6.4.10, BiP, Binding-immunoglobulin protein, 78 kDa glucose-regulated protein
Anti-HSPA5 Antibody (2X960) 是一种 Mouse 抗体，靶向 HSPA5。Anti-HSPA5 Antibody (2X960) 可用于 WB,ICC,IHC。
Anti-HSPA5 Antibody (2X960)
Anti-HSPA5 Antibody (2X960)
还可以产品编号 TMAC-01726 别名 Immunoglobulin heavy chain-binding protein, HSPA 5, HSP70 family protein 5, Heat shock protein family A member 5, Heat shock protein 70 family protein 5, GRP-78, GRP78, Endoplasmic reticulum chaperone BiP, EC 3.6.4.10, BiP, Binding-immunoglobulin protein, 78 kDa glucose-regulated protein
Anti-HSPA5 Antibody (2X960) 是一种 Mouse 抗体，靶向 HSPA5。Anti-HSPA5 Antibody (2X960) 可用于 WB,ICC,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,985 | 5日内发货 | |
| 100 μL | ¥ 2,995 | 5日内发货 |
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偶联与修饰
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| 产品描述 | Anti-HSPA5 Antibody (2X960) is a Mouse antibody targeting HSPA5. Anti-HSPA5 Antibody (2X960) can be used in WB,ICC,IHC. |
| 别名 | Immunoglobulin heavy chain-binding protein, HSPA 5, HSP70 family protein 5, Heat shock protein family A member 5, Heat shock protein 70 family protein 5, GRP-78, GRP78, Endoplasmic reticulum chaperone BiP, EC 3.6.4.10, BiP, Binding-immunoglobulin protein, 78 kDa glucose-regulated protein |
| 交叉反应 | Human,Mouse |
| 验证活性 | 1. Western blot analysis on cell lysates using anti- GRP78 mouse mAb. 2. ICC staining GRP78 in MCF-7 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining GRP78 in HepG2 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:2000-5000; ICC: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Binding immunoglobulin protein (BiP) also known as 78 kDa glucose-regulated protein (GRP-78) or heat shock 70 kDa protein 5 (HSPA5) is a protein that in humans is encoded by the HSPA5 gene. BiP is a HSP70 molecular chaperone located in the lumen of the endoplasmic reticulum (ER) that binds newly synthesized proteins as they are translocated into the ER, and maintains them in a state competent for subsequent folding and oligomerization. BiP is also an essential component of the translocation machinery, as well as playing a role in retrograde transport across the ER membrane of aberrant proteins destined for degradation by the proteasome. Like many stress and heat shock proteins, BiP/GRP78 has potent immunological activity when released from the internal environment of the cell into the extracelluar space.specifically, it feeds inflammatory and pro-resolutory signals into immune networks, thus helping to resolve inflammation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 78 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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