Name: BTN3A2 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-04779
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 429

3日内发货

10 μg

¥ 697

3日内发货

20 μg

¥ 1,150

3日内发货

50 μg

¥ 2,260

3日内发货

100 μg

¥ 3,820

现货

200 μg

¥ 6,750

5日内发货

500 μg

¥ 14,200

5日内发货

生物活性

产品描述	The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted evolution of BTN3 characterized by a strong and recurrent homogenization of the region encoding the signal peptide and the immunoglobulin variable (IgV) domain in Hominoids, where the sequences of BTN3A1 or BTN3A3 are replaced by BTN3A2 sequence.
生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted evolution of BTN3 characterized by a strong and recurrent homogenization of the region encoding the signal peptide and the immunoglobulin variable (IgV) domain in Hominoids, where the sequences of BTN3A1 or BTN3A3 are replaced by BTN3A2 sequence.
种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	P78410-1
蛋白构建	A DNA sequence encoding the human BTN3A2 (NP_008978.2) (Met1-Trp248) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Gln 30
蛋白纯度	> 95 % as determined by SDS-PAGE.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	CD277, butyrophilin subfamily 3 member A2, BTN3.2, BTF4, BTF3, BT3.2
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	25.1 kDa (predicted)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

BTN3A2 Protein, Human, Recombinant (His)

BTN3A2 Protein, Human, Recombinant (His)

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