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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-AVEN Polyclonal Antibody

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货号 TMAB-02979

Anti-AVEN Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AVEN。Anti-AVEN Polyclonal Antibody 可用于 WB。

Anti-AVEN Polyclonal Antibody

Anti-AVEN Polyclonal Antibody

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货号 TMAB-02979

Anti-AVEN Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AVEN。Anti-AVEN Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-AVEN Polyclonal Antibody is a Rabbit antibody targeting AVEN. Anti-AVEN Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Pig,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endomembrane system; Peripheral membrane protein. Note=Associated with intracellular membranes.
组织特异性Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. AVEN is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that AVEN functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that AVEN impedes Apaf-1-mediated caspase activation. Higher levels of AVEN mRNA are seen in patients with acute leukemia than in control patients, suggesting that AVEN may be useful as a prognostic indicator in leukemia patients.
抗原信息
免疫原
KLH conjugated synthetic peptide: human AVEN
抗原种属
Human
基因名称
AVEN
基因ID
57099
蛋白名称
Cell death regulator Aven
Uniprot ID
Q9NQS1
功能
Protects against apoptosis mediated by Apaf-1
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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