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Anti-AKR1C3 Antibody (1D105)

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货号 TMAB-02410

Anti-AKR1C3 Antibody (1D105) 是一种 Rabbit 抗体，靶向 AKR1C3。Anti-AKR1C3 Antibody (1D105) 可用于 WB,ICC/IF,IP,FCM。

Anti-AKR1C3 Antibody (1D105)

Anti-AKR1C3 Antibody (1D105)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02410

Anti-AKR1C3 Antibody (1D105) 是一种 Rabbit 抗体，靶向 AKR1C3。Anti-AKR1C3 Antibody (1D105) 可用于 WB,ICC/IF,IP,FCM。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-AKR1C3 Antibody (1D105) is a Rabbit antibody targeting AKR1C3. Anti-AKR1C3 Antibody (1D105) can be used in WB,ICC/IF,IP,FCM.
Ig Type
IgG
克隆号
1D105
反应种属
Human,Mouse,Rat
应用WBICC/IFIPFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. The dominant HSD in prostate and mammary gland. In the prostate, higher levels in epithelial cells than in stromal cells. In the brain, expressed in medulla, spinal cord, frontotemporal lobes, thalamus, subthalamic nuclei and amygdala. Weaker expression in the hippocampus, substantia nigra and caudate.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Cytosolic aldo-keto reductase that catalyzes the NADH and NADPH-dependent reduction of ketosteroids to hydroxysteroids. Acts as a NAD(P)(H)-dependent 3-, 17- and 20-ketosteroid reductase on the steroid nucleus and side chain and regulates the metabolism of androgens, estrogens and progesterone.
抗原信息
免疫原
A synthesized peptide: human AKR1C3
抗原种属
Human
基因名称
AKR1C3
基因ID
8644
蛋白名称
Aldo-keto reductase family 1 member C3
Uniprot ID
P42330
功能
Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone.
化学信息
分子量Theoretical: 37 kDa. Actual: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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