购物车
- 全部删除
您的购物车当前为空
Anti-MMP-9 Antibody-Biotin (5X385)
还可以产品编号 TMAY-00613B
Anti-MMP-9 Antibody-Biotin (5X385) 是一种 Biotin-conjugated Rabbit 抗体，靶向 MMP-9。Anti-MMP-9 Antibody-Biotin (5X385) 可用于 ELISA。
Anti-MMP-9 Antibody-Biotin (5X385)
Anti-MMP-9 Antibody-Biotin (5X385)
还可以产品编号 TMAY-00613B
Anti-MMP-9 Antibody-Biotin (5X385) 是一种 Biotin-conjugated Rabbit 抗体，靶向 MMP-9。Anti-MMP-9 Antibody-Biotin (5X385) 可用于 ELISA。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-MMP-9 Antibody-Biotin (5X385) is a Biotin-conjugated Rabbit antibody targeting MMP-9. Anti-MMP-9 Antibody-Biotin (5X385) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5X385 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human matrix metallopeptidase 9 (rh MMP-9; TMPY-00888; Met 1-Asp 707; NP_004985.2) and then biotinylated. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. MMP9, also known as 92-kDa gelatinase B/type IV collagenase, is secreted from neutrophils, macrophages, and some transformed cells, and is the most complex family member in terms of domain structure and regulation of its activity. It plays an important role in tissue remodeling in normal and pathological inflammatory processes. MMP-9 is a major secretion product of macrophages and a component of cytoplasmic granules of neutrophils and is particularly important in the pathogenesis of inflammatory, infectious, and neoplastic diseases in many organs including the lung. This enzyme is also secreted by lymphocytes and stromal cells upon stimulation by inflammatory cytokines, or upon delivery of bi-directional activation signals following integrin-mediated cell-cell or cell-extracellular matrix (ECM) contacts. Since the integrity of the tissue architecture is closely dependent on the delicate balance between MMPs and their inhibitors, excessive production of MMP-9 is linked to tissue damage and degenerative inflammatory disorders. As a consequence, regulation of gene transcription and tissue-specific expression of MMP-9 in normal and diseased states are being actively investigated to pave the way for new therapeutic targets. Besides, the dramatic overexpression of MMP-9 in cancer and various inflammatory conditions points to the molecular mechanisms controlling its expression as a potential target for eventual rational therapeutic intervention. |
| 偶联 | Biotin |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human MMP-9 protein (TMPY-00888) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-MMP-9 Antibody-Biotin (5X385) | purchase Anti-MMP-9 Antibody-Biotin (5X385) | Anti-MMP-9 Antibody-Biotin (5X385) cost | order Anti-MMP-9 Antibody-Biotin (5X385)
嗨！有任何问题？点我咨询
评论内容