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Anti-PKHD1 Antibody (4M854)
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产品编号 TMAC-03349
别名 Tigmin, TIGM1, Polyductin, Polycystic kidney and hepatic disease 1 protein, PKHD1_HUMAN, PKHD 1, FPC, Fibrocystin, FCYT, ARPKD
Anti-PKHD1 Antibody (4M854) 是一种 Mouse 抗体，靶向 PKHD1。Anti-PKHD1 Antibody (4M854) 可用于 WB,ICC,IHC,FCM。
Anti-PKHD1 Antibody (4M854)
Anti-PKHD1 Antibody (4M854)
还可以产品编号 TMAC-03349 别名 Tigmin, TIGM1, Polyductin, Polycystic kidney and hepatic disease 1 protein, PKHD1_HUMAN, PKHD 1, FPC, Fibrocystin, FCYT, ARPKD
Anti-PKHD1 Antibody (4M854) 是一种 Mouse 抗体，靶向 PKHD1。Anti-PKHD1 Antibody (4M854) 可用于 WB,ICC,IHC,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,980 | 5日内发货 | |
| 100 μL | ¥ 2,995 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-PKHD1 Antibody (4M854) is a Mouse antibody targeting PKHD1. Anti-PKHD1 Antibody (4M854) can be used in WB,ICC,IHC,FCM. |
| 别名 | Tigmin, TIGM1, Polyductin, Polycystic kidney and hepatic disease 1 protein, PKHD1_HUMAN, PKHD 1, FPC, Fibrocystin, FCYT, ARPKD |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of PKHD1 on mouse PKHD1 recombinant protein using anti-PKHD1 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissue using anti-PKHD1 antibody. Counter stained with hematoxylin. 3. ICC staining PKHD1 (green) and Actin filaments (red) in A431 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. Flow cytometric analysis of Hela cells with PKHD1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | May be required for correct bipolar cell division through the regulation of centrosome duplication and mitotic spindle assembly. May be a receptor protein that acts in collecting-duct and biliary differentiation. Defects in PKHD1 are the cause of polycystic kidney disease autosomal recessive (ARPKD). ARPKD is a severe form of polycystic kidney disease affecting the kidneys and the hepatic biliary tract. The clinical spectrum is widely variable, with most cases presenting during infancy. The fetal phenotypic features classically include enlarged and echogenic kidneys, as well as oligohydramnios secondary to a poor urine output. Up to 50% of the affected neonates die shortly after birth, as a result of severe pulmonary hypoplasia and secondary respiratory insufficiency. In the subset that survives the perinatal period, morbidity and mortality are mainly related to severe systemic hypertension, renal insufficiency, and portal hypertension due to portal-tract fibrosis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 445 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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