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Anti-IL-10R beta/IL-10RB Antibody (6Y486)
还可以产品编号 TMAY-01368
Anti-IL-10R beta/IL-10RB Antibody (6Y486) 是一种 Mouse 抗体，靶向 IL-10R beta/IL-10RB。Anti-IL-10R beta/IL-10RB Antibody (6Y486) 可用于 ELISA。
Anti-IL-10R beta/IL-10RB Antibody (6Y486)
Anti-IL-10R beta/IL-10RB Antibody (6Y486)
还可以产品编号 TMAY-01368
Anti-IL-10R beta/IL-10RB Antibody (6Y486) 是一种 Mouse 抗体，靶向 IL-10R beta/IL-10RB。Anti-IL-10R beta/IL-10RB Antibody (6Y486) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IL-10R beta/IL-10RB Antibody (6Y486) is a Mouse antibody targeting IL-10R beta/IL-10RB. Anti-IL-10R beta/IL-10RB Antibody (6Y486) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 6Y486 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL10RB extracellular domain (rh IL10RB; TMPY-01236; NP_000619.3; Met 1-Ser 220). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 0.02% Tween 80, pH 7.0 |
| 研究背景 | Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 receptor. IL10RB/IL-10RB belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins is required for IL10-induced signal transduction. Defects in IL10RB/IL-10RB are the cause of inflammatory bowel disease type 25 (IBD25). It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn's disease and ulcerative colitis phenotypes. Crohn's disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IL10RB protein (TMPY-01236) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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