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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RNF20 Polyclonal Antibody

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货号 TMAB-12309

Anti-RNF20 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RNF20。Anti-RNF20 Polyclonal Antibody 可用于 WB。

Anti-RNF20 Polyclonal Antibody

Anti-RNF20 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12309

Anti-RNF20 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RNF20。Anti-RNF20 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-RNF20 Polyclonal Antibody is a Rabbit antibody targeting RNF20. Anti-RNF20 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nuclear
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景RNF20 is an E3 ubiquitin ligase protein that mediates monoubiquitination of histone H2B and the methylation of histone H3. It forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code and gene regulation. It is required for transcriptional activation of Hox genes. It is recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RNF20
抗原种属
Human
基因名称
RNF20
基因ID
56254
蛋白名称
E3 ubiquitin-protein ligase BRE1A
Uniprot ID
Q5VTR2
功能
Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator.
化学信息
分子量Theoretical: 114 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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