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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SUZ12 Antibody (4D889)

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货号 TMAB-13290

Anti-SUZ12 Antibody (4D889) 是一种 Rabbit 抗体，靶向 SUZ12。Anti-SUZ12 Antibody (4D889) 可用于 WB。

Anti-SUZ12 Antibody (4D889)

Anti-SUZ12 Antibody (4D889)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13290

Anti-SUZ12 Antibody (4D889) 是一种 Rabbit 抗体，靶向 SUZ12。Anti-SUZ12 Antibody (4D889) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-SUZ12 Antibody (4D889) is a Rabbit antibody targeting SUZ12. Anti-SUZ12 Antibody (4D889) can be used in WB.
Ig Type
IgG
克隆号
4D889
反应种属
Human,Mouse,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Overexpressed in breast and colon cancer.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景UZ12 is a polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. SUZ12 is a component of the PRC2 complex, which methylates Lys-9 and Lys-27 residues of histone H3. SUZ12 is a component of the PRC2 complex, composed of EED, EZH2, SUZ12/JJAZ1, RBBP4 and RBBP7. This complex is distinct from the PRC1 complex, which contains many other PcG proteins like BMI1, CBX4, CBX8, PHC2, PHC3, SCMH1, RING1 and RNF2. SUZ12 mRNA is upregulated in a number of tumors including breast and colon.
抗原信息
免疫原
A synthesized peptide: human SUZ12
抗原种属
Human
基因名称
SUZ12
基因ID
23512
蛋白名称
Polycomb protein SUZ12
Uniprot ID
Q15022
功能
Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
化学信息
分子量Theoretical: 83 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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