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顶部生物活性储存和溶解信息计算器

Anti-Desmin Antibody (6C49)

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产品编号 TMAY-00114

别名 Desmin, DES

Anti-Desmin Antibody (6C49) 是一种 Mouse 抗体，靶向 Desmin。Anti-Desmin Antibody (6C49) 可用于 IHC-P。

Anti-Desmin Antibody (6C49)

Anti-Desmin Antibody (6C49)

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Rating icon 还可以
产品编号 TMAY-00114 别名 Desmin, DES

Anti-Desmin Antibody (6C49) 是一种 Mouse 抗体，靶向 Desmin。Anti-Desmin Antibody (6C49) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 1,684
5日内发货
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产品介绍

生物活性
产品描述
Anti-Desmin Antibody (6C49) is a Mouse antibody targeting Desmin. Anti-Desmin Antibody (6C49) can be used in IHC-P.
别名Desmin, DES
Ig Type
Mouse IgG1
克隆号
6C49
交叉反应
Human
特异性
Human
Mouse, Rat (Species predicted to react based on 100% sequence homology)
验证活性
1. Immunochemical staining of human Desmin in human heart with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
2. Immunochemical staining of human Desmin in human smooth muscle with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
应用IHC-P
推荐剂量
IHC-P: 1:30-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the C-terminus of the Human Desmin. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The cohesin loading factor, nipped-B-like protein (NIPBL), is also known as the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contributes to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation. Downregulation of NIPBL arrested cells in the G0/G1 phase of the cell cycle and induced apoptosis and autophagy of breast cancer cells through the caspase3 and mammalian target of rapamycin (mTOR) signaling pathways. NIPBL, the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contributes to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: C-terminus of the Human Desmin
抗原种属
Human
研究领域
Cardiac Stem Cell Markers
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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