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Anti-Desmin Antibody (6C49)
还可以产品编号 TMAY-00114
Anti-Desmin Antibody (6C49) 是一种 Mouse 抗体，靶向 Desmin。Anti-Desmin Antibody (6C49) 可用于 IHC-P。
Anti-Desmin Antibody (6C49)
Anti-Desmin Antibody (6C49)
还可以产品编号 TMAY-00114
Anti-Desmin Antibody (6C49) 是一种 Mouse 抗体，靶向 Desmin。Anti-Desmin Antibody (6C49) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Desmin Antibody (6C49) is a Mouse antibody targeting Desmin. Anti-Desmin Antibody (6C49) can be used in IHC-P. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 6C49 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human Desmin in human heart with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human Desmin in human smooth muscle with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:30-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the C-terminus of the Human Desmin. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The cohesin loading factor, nipped-B-like protein (NIPBL), is also known as the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contributes to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation. Downregulation of NIPBL arrested cells in the G0/G1 phase of the cell cycle and induced apoptosis and autophagy of breast cancer cells through the caspase3 and mammalian target of rapamycin (mTOR) signaling pathways. NIPBL, the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contributes to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the C-terminus of the Human Desmin |
| 抗原种属 | Human |
| 研究领域 | Cardiac Stem Cell Markers |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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