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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GABPB2 Polyclonal Antibody

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货号 TMAB-06253

Anti-GABPB2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GABPB2。Anti-GABPB2 Polyclonal Antibody 可用于 WB。

Anti-GABPB2 Polyclonal Antibody

Anti-GABPB2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06253

Anti-GABPB2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GABPB2。Anti-GABPB2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-GABPB2 Polyclonal Antibody is a Rabbit antibody targeting GABPB2. Anti-GABPB2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Cow,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, GABP beta. GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini. In primary neuronal cultures, GABP beta is expressed in both the cytoplasm and the nucleus, whereas GABP alpha is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo . The GABP alpha beta tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GABPB2/GABPB1
抗原种属
Human
基因名称
GABPB1
基因ID
2553
蛋白名称
GA-binding protein subunit beta-1
Uniprot ID
Q06547
功能
Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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