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Anti-B7-1 Antibody (4I630)
还可以产品编号 TMAY-01080
Anti-B7-1 Antibody (4I630) 是一种 Mouse 抗体，靶向 B7-1。Anti-B7-1 Antibody (4I630) 可用于 ELISA,FCM。
Anti-B7-1 Antibody (4I630)
Anti-B7-1 Antibody (4I630)
还可以产品编号 TMAY-01080
Anti-B7-1 Antibody (4I630) 是一种 Mouse 抗体，靶向 B7-1。Anti-B7-1 Antibody (4I630) 可用于 ELISA,FCM。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-B7-1 Antibody (4I630) is a Mouse antibody targeting B7-1. Anti-B7-1 Antibody (4I630) can be used in ELISA,FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4I630 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human B7-1(CD80) expression on Daudi cells. Cells were stained with purified anti-Human B7-1(CD80), then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | ELISA,FCM |
| 推荐剂量 | ELISA: 1:1000-1:2000; FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD80 / B7-1 (rh CD80 / B7-1; TMPY-01063; Met 1-Asn 242; NP_005182.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. As costimulatory ligands, B7-1 which exists predominantly as dimer and the related protein B7-2, interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus constitute one of the dominant pathways that regulate T cell activation and tolerance, cytokine production, and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human CD80 / B7-1 Protein (TMPY-01063) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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