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Anti-interferon alpha 5/IFNA5 Antibody (1Q35) 是一种 Mouse 抗体,靶向 interferon alpha 5/IFNA5。Anti-interferon alpha 5/IFNA5 Antibody (1Q35) 可用于 ELISA。
Anti-interferon alpha 5/IFNA5 Antibody (1Q35) 是一种 Mouse 抗体,靶向 interferon alpha 5/IFNA5。Anti-interferon alpha 5/IFNA5 Antibody (1Q35) 可用于 ELISA。
产品描述 | Anti-interferon alpha 5/IFNA5 Antibody (1Q35) is a Mouse antibody targeting interferon alpha 5/IFNA5. Anti-interferon alpha 5/IFNA5 Antibody (1Q35) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 1Q35 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human interferon-alpha/IFNA5 (rh interferon-alpha/IFNA5; P01569Met1-Glu189). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as an important regulator of growth and differentiation, affecting cellular communication and signal transduction pathways as well as immunological control. Originally discovered as an antiviral substance, the efficacy of IFN-alpha in malignant, viral, immunological, angiogenic, inflammatory, and fibrotic diseases suggests a spectrum of interrelated pathophysiologies. IFN-alpha emerged as a prototypic tumor suppressor protein that represses the clinical tumorigenic phenotype in some malignancies capable of differentiation. |
偶联 | Unconjugated |
免疫原 | Recombinant Human interferon-alpha/IFNA5 Protein |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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