购物车
- 全部删除
您的购物车当前为空
Anti-IGF1/IGF-I Antibody (9D219)
还可以产品编号 TMAH-00598
别名 胰岛素样生长因子, somatomedin C, MGF, insulin-like growth factor 1, IGF‑I, IGF-I, IGFI, IGF1A, IGF-1
Anti-IGF1/IGF-I Antibody (9D219) 是一种抗体，靶向 IGF1/IGF-I。Anti-IGF1/IGF-I Antibody (9D219) 可用于 ELISA, IHC。
Anti-IGF1/IGF-I Antibody (9D219)
Anti-IGF1/IGF-I Antibody (9D219)
还可以产品编号 TMAH-00598 别名 胰岛素样生长因子, somatomedin C, MGF, insulin-like growth factor 1, IGF‑I, IGF-I, IGFI, IGF1A, IGF-1
Anti-IGF1/IGF-I Antibody (9D219) 是一种抗体，靶向 IGF1/IGF-I。Anti-IGF1/IGF-I Antibody (9D219) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IGF1/IGF-I Antibody (9D219) is an antibody targeting IGF1/IGF-I. Anti-IGF1/IGF-I Antibody (9D219) can be used in ELISA, IHC. |
| 别名 | 胰岛素样生长因子, somatomedin C, MGF, insulin-like growth factor 1, IGF‑I, IGF-I, IGFI, IGF1A, IGF-1 |
| Ig Type | hIgG2 |
| 克隆号 | 9D219 |
| 交叉反应 | Human |
| 验证活性 | 1. IHC image of TMAH-00598 diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Human IgG labeled by HRP and visualized using 0.05% DAB. 2. IHC image of TMAH-00598 diluted at 1:100 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Human IgG labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human IGF1 Protein |
| 抗原种属 | Human |
| 基因ID | 3479 |
| Uniprot ID | |
| 研究领域 | Cancer, Developmental biology, Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-IGF1/IGF-I Antibody (9D219) | purchase Anti-IGF1/IGF-I Antibody (9D219) | Anti-IGF1/IGF-I Antibody (9D219) cost | order Anti-IGF1/IGF-I Antibody (9D219)
嗨！有任何问题？点我咨询
评论内容