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CCR4 Protein, Human, Recombinant (His & SUMO)

CCR4 Protein, Human, Recombinant (His & SUMO)

产品编号 TMPH-01064
别名: CMKBR4, CD194, K5-5, CCR-4, C-C chemokine receptor type 4, CC-CKR-4, CCR4, C-C CKR-4

High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 19.0 kDa and the accession number is P51679.

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CCR4 Protein, Human, Recombinant (His & SUMO)
规格 价格/CNY 货期 数量
20 μg ¥ 1,510 20日内发货
100 μg ¥ 2,840 20日内发货
1 mg ¥ 12,200 20日内发货
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产品目录号及名称: CCR4 Protein, Human, Recombinant (His & SUMO) (TMPH-01064)
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产品描述 High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 19.0 kDa and the accession number is P51679.
种属 Human
表达系统 E. coli
标签 N-6xHis-SUMO
蛋白编号 P51679
别名 CMKBR4, CD194, K5-5, CCR-4, C-C chemokine receptor type 4, CC-CKR-4, CCR4, C-C CKR-4
氨基酸序列 EKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDAL
蛋白构建 309-360 aa
蛋白纯度 > 85% as determined by SDS-PAGE.
分子量 19.0 kDa (predicted)
缓冲液 If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

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Keywords

CCR4 Protein, Human, Recombinant (His & SUMO) CMKBR4 CD194 K5-5 CCR-4 C-C chemokine receptor type 4 CC-CKR-4 CCR4 C-C CKR-4 recombinant recombinant-proteins proteins protein

 

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