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Anti-CA9/Carbonic Anhydrase IX Antibody (4F130)

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Anti-CA9/Carbonic Anhydrase IX Antibody (4F130)
产品编号 TMAY-00272
别名 RCC, PMW1, P54/58N, MN, G250, EC 4.2.1.1, Carbonic Anhydrase IX, CA-IX, CAIX, CA9

Anti-CA9/Carbonic Anhydrase IX Antibody (4F130) 是一种 Rabbit 抗体，靶向 CA9/Carbonic Anhydrase IX。Anti-CA9/Carbonic Anhydrase IX Antibody (4F130) 可用于 FCM。

Anti-CA9/Carbonic Anhydrase IX Antibody (4F130)
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Anti-CA9/Carbonic Anhydrase IX Antibody (4F130)

Rating icon 还可以
Anti-CA9/Carbonic Anhydrase IX Antibody (4F130)
产品编号 TMAY-00272 别名 RCC, PMW1, P54/58N, MN, G250, EC 4.2.1.1, Carbonic Anhydrase IX, CA-IX, CAIX, CA9

Anti-CA9/Carbonic Anhydrase IX Antibody (4F130) 是一种 Rabbit 抗体，靶向 CA9/Carbonic Anhydrase IX。Anti-CA9/Carbonic Anhydrase IX Antibody (4F130) 可用于 FCM。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-CA9/Carbonic Anhydrase IX Antibody (4F130) is a Rabbit antibody targeting CA9/Carbonic Anhydrase IX. Anti-CA9/Carbonic Anhydrase IX Antibody (4F130) can be used in FCM.
别名RCC, PMW1, P54/58N, MN, G250, EC 4.2.1.1, Carbonic Anhydrase IX, CA-IX, CAIX, CA9
Ig Type
Rabbit IgG
克隆号
4F130
交叉反应
Human
验证活性
Flow cytometric analysis of Human CAIX expression on Hela cells. Cells were stained with purified anti-Human CAIX, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Carbonic Anhydrase IX/CA9 (rh Carbonic Anhydrase IX/CA9; TMPY-00690; NP_001207.2; Met1-Asp414).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
其他可选修饰符
FITC/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Human Carbonic Anhydrase IX/CA9 Protein (TMPY-00690)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

PMW-1PMW 1G-250G 250CA-9CA 9

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