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Anti-CAMKII alpha Antibody (4A308) 是一种 Rabbit 抗体,靶向 CAMKII alpha。Anti-CAMKII alpha Antibody (4A308) 可用于 WB,IP,FCM。
Anti-CAMKII alpha Antibody (4A308) 是一种 Rabbit 抗体,靶向 CAMKII alpha。Anti-CAMKII alpha Antibody (4A308) 可用于 WB,IP,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-CAMKII alpha Antibody (4A308) is a Rabbit antibody targeting CAMKII alpha. Anti-CAMKII alpha Antibody (4A308) can be used in WB,IP,FCM. |
别名 | zgc:123320, zgc:112538, R74975, PK2CDD, mKIAA0968, MGC155201, MGC139375, MGC123320, KIAA0968, KCC2A, EC 2.7.11.17, CaMK-II subunit alpha, CaMKII alpha, CaMKII, CAMKB, CAMKA, CAMK2D, CAMK2A, CaMK II delta subunit, CaMK II beta subunit, CaMK II alpha subunit, CAM2, CaM kinase II subunit alpha, CaM kinase II delta subunit, CaM kinase II delta chain, CaM kinase II beta subunit, CaM kinase II beta chain, CaM kinase II alpha subunit, CaM kinase II alpha chain, Calcium/calmodulin-dependent protein kinase(CaM kinase) II alpha, Calcium/calmodulin-dependent protein kinase type IIA, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Calcium/Calmodulin Dependent Protein Kinase II G, Calcium/calmodulin dependent protein kinase II alpha, Calcium calmodulin dependent protein kinase II alpha-B subunit, Calcium calmodulin dependent protein kinase II, Calcium calmodulin dependent protein kinase CaM kinase II alpha, alpha CaMKII |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of CaMKII alpha on rat brain cells lysates using anti-CaMKII alpha antibody at 1/500 dilution. 2. Flow cytometric analysis of SH-SY5Y cells with CaMKII alpha antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the _x0018_secondary antibody. |
应用 | |
推荐剂量 | WB: 1:1000-2000; IP: 1:10-50; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes designated α, β, γ and δ, which may or may not be co-expressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation. Stimulation of the T cell receptor CD3 signaling complex with an CD3 monoclonal antibody leads to a 10-40 fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory Threonine residue at position 177. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 54 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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