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Sodium dodecyl sulfate

Name: Sodium dodecyl sulfate
Brand: TargetMol
SKU: T20075
Price: 163 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.75%

货号 T20075Cas号 151-21-3

别名月桂基硫酸钠盐, 十二烷基硫酸钠, Sodium lauryl sulfate, Sodium dodecylsulfate, SDS, NSC-402488, NSC402488, NSC 402488, Natrium laurylsulfuricum, Laurylsulfuric acid sodium salt, Anticerumen

Sodium dodecyl sulfate(Sodium lauryl sulfate) 是一种作药用辅料，无生物活性，单能提高药物制剂的稳定性、溶解性和加工性。

Sodium dodecyl sulfate

一键复制产品信息

很棒

纯度: 99.75%

货号 T20075 别名月桂基硫酸钠盐, 十二烷基硫酸钠, Sodium lauryl sulfate, Sodium dodecylsulfate, SDS, NSC-402488, NSC402488, NSC 402488, Natrium laurylsulfuricum, Laurylsulfuric acid sodium salt, AnticerumenCas号 151-21-3

Sodium dodecyl sulfate(Sodium lauryl sulfate) 是一种作药用辅料，无生物活性，单能提高药物制剂的稳定性、溶解性和加工性。

规格	价格	库存	数量
25 g	¥ 163	现货

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

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纯度: 99.75%

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COA LCMS HNMR 产品操作手册

产品介绍

Sodium dodecyl sulfate AI Summary

Sodium dodecyl sulfate exhibits a diverse range of biological activities. It demonstrates a dose-dependent hemolytic effect on rat red blood cells, with hemolysis increasing from 12.25% at 1 mM concentration to 62.66% at 5 mM. In antimicrobial studies, it shows significant activity against various strains of Escherichia coli, including multidrug-resistant strains, with Minimum Inhibitory Concentration (MIC) values ranging from 62.5 µg/mL to 128.0 µg/mL. It also exhibits antibacterial activity against Enterobacter cloacae, Enterococcus faecalis, Proteus mirabilis, and methicillin-resistant Staphylococcus aureus, and antifungal activity against Candida species. Additionally, it has potent anti-inflammatory properties by inhibiting IL1alpha release in a reconstituted human epidermis model. In terms of cytotoxicity, Sodium dodecyl sulfate is highly potent against human HepG2/C3A cells with an IC50 value of 0.222 nM, and it shows lesser toxicity against mouse RAW264.7 and human HCT116 cells, with IC50 values greater than 100,000 nM. The compound also presents impacting activities against Steinernema feltiae in nematicidal assays and induces membrane permeabilization. Biosurfactant properties are indicated by its ability to lower surface tension, with a critical micelle concentration (CMC) of 8.2 mM and activity in oil displacement assays. Furthermore, it displays significant inhibition of full-length human soluble epoxide hydrolase phosphatase activity, stabilizing the phosphatase domain while showing weaker activity against the hydrolase domain. Sodium dodecyl sulfate's broad spectrum of activities position it as a potential candidate for therapeutic applications involving antimicrobial, anti-inflammatory, and cytotoxic properties..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Sodium dodecyl sulfate(Sodium lauryl sulfate) is a pharmaceutical excipient that is biologically inactive and improves the stability, solubility and processability of pharmaceutical preparations.
别名	月桂基硫酸钠盐, 十二烷基硫酸钠, Sodium lauryl sulfate, Sodium dodecylsulfate, SDS, NSC-402488, NSC402488, NSC 402488, Natrium laurylsulfuricum, Laurylsulfuric acid sodium salt, Anticerumen

化学信息

分子量	288.38
分子式	C₁₂H₂₅NaO₄S
CAS No.	151-21-3
Smiles	O=S([O-])(OCCCCCCCCCCCC)=O.[Na+]
密度	1.03 g/cm3 at 20℃

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度信息

DMSO: 60 mg/mL (208.06 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4676 mL	17.3382 mL	34.6765 mL	173.3823 mL
5 mM	0.6935 mL	3.4676 mL	6.9353 mL	34.6765 mL
10 mM	0.3468 mL	1.7338 mL	3.4676 mL	17.3382 mL
20 mM	0.1734 mL	0.8669 mL	1.7338 mL	8.6691 mL
50 mM	0.0694 mL	0.3468 mL	0.6935 mL	3.4676 mL
100 mM	0.0347 mL	0.1734 mL	0.3468 mL	1.7338 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法： 取 100 μL DMSO 母液，添加 400 μL PEG300 混匀澄清，再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH₂O 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

关键词

Sodium lauryl Sulfate

Sodium dodecyl sulfate

Sodium dodecyl sulfate