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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PEDF Polyclonal Antibody 3

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货号 TMAB-10161

Anti-PEDF Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 PEDF。Anti-PEDF Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,IF。

Anti-PEDF Polyclonal Antibody 3

Anti-PEDF Polyclonal Antibody 3

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Rating icon 还可以
货号 TMAB-10161

Anti-PEDF Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 PEDF。Anti-PEDF Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-PEDF Polyclonal Antibody 3 is a Rabbit antibody targeting PEDF. Anti-PEDF Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted. Melanosome. Enriched in stage I melanosomes.
组织特异性Retinal pigment epithelial cells and blood plasma.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Pigment epithelium derived factor, originally identified in conditioned medium of cultured human fetal retinal pigment epithelial (RPE) cells, is a neurotrophic protein that induces extensive neuronal differentiation in human Y79 retinoblastoma cells, a neoplastic counterpart of normal retinoblasts. It has been suggested that PEDF is synthesized by RPE cells and secreted into the retina interphotoreceptor matrix where it may influence development/differentiation of the neural retina. PEDF is a potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. The PEDF gene is a member of the serpin gene family. Serpins are a group of serine protease inhibitors, some of which have also been reported to exhibit neurotrophic activity.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PEDF
抗原种属
Human
基因名称
SERPINF1
基因ID
5176
蛋白名称
Pigment epithelium-derived factor
Uniprot ID
P36955
功能
Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
化学信息
分子量Theoretical: 46 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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