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Anti-SORCS2 Polyclonal Antibody

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货号 TMAB-13046

Anti-SORCS2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SORCS2。Anti-SORCS2 Polyclonal Antibody 可用于 WB。

Anti-SORCS2 Polyclonal Antibody

Anti-SORCS2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13046

Anti-SORCS2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SORCS2。Anti-SORCS2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-SORCS2 Polyclonal Antibody is a Rabbit antibody targeting SORCS2. Anti-SORCS2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single pass type I membrane protein.
组织特异性Highly expressed in brain and kidney. Detected at low levels in heart, liver, small intestine, skeletal muscle and thymus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景There are three SorCS genes that have diverse, partially overlapping functions in the central nervous system. In the developing and mature central nervous system, SorCS1, SorCS2 and SorCS3 genes are expressed in a combinatorial, non-overlapping pattern. SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, based on a common VPS10 domain, which is the hallmark of the SorCS receptor family. SorCS2 (sortilin-related VPS10 domain containing receptor 2) is a 1,150 amino acid single-pass type I membrane protein that is highly expressed in brain and kidney. Containing six BNR repeats and a single PKD domain, SorCS2 is encoded by a gene that maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SORCS2
抗原种属
Human
基因名称
SORCS2
基因ID
蛋白名称
VPS10 domain-containing receptor SorCS2
Uniprot ID
功能
SORCS2 is a member of the vacuolar protein sorting 10 (VPS10) domain containing receptor protein family. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. These proteins are strongly expressed in the central nervous system.
化学信息
分子量Theoretical: 123 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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