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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-TRIM25 (Ser100) Polyclonal Antibody

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货号 TMAB-11388

Anti-Phospho-TRIM25 (Ser100) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-TRIM25 (Ser100)。Anti-Phospho-TRIM25 (Ser100) Polyclonal Antibody 可用于 WB。

Anti-Phospho-TRIM25 (Ser100) Polyclonal Antibody

Anti-Phospho-TRIM25 (Ser100) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11388

Anti-Phospho-TRIM25 (Ser100) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-TRIM25 (Ser100)。Anti-Phospho-TRIM25 (Ser100) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-TRIM25 (Ser100) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TRIM25 (Ser100). Anti-Phospho-TRIM25 (Ser100) Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性Ubiquitous.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human TRIM25 around the phosphorylation site of Ser100
抗原种属
Human
基因名称
TRIM25
基因ID
7706
蛋白名称
E3 ubiquitin/ISG15 ligase TRIM25
Uniprot ID
Q14258
功能
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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