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Anti-Phospho-p53 (Ser15) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-p53 (Ser15)。Anti-Phospho-p53 (Ser15) Polyclonal Antibody 可用于 WB,IHC,IP,IF,ELISA。
Anti-Phospho-p53 (Ser15) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-p53 (Ser15)。Anti-Phospho-p53 (Ser15) Polyclonal Antibody 可用于 WB,IHC,IP,IF,ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-p53 (Ser15) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p53 (Ser15). Anti-Phospho-p53 (Ser15) Polyclonal Antibody can be used in WB,IHC,IP,IF,ELISA. |
别名 | p-p53 (Ser15), p-p53 (S15), p53 (p-Ser15), p53 (p-S15) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from 293 cells untreated or treated with UV using p53 (Phospho-Ser15) Antibody TMAC-02995. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p53 (Phospho-Ser15) Antibody TMAC-02995 (left) or the same antibody preincubated with blocking peptide (right). 3. Immunofluorescence staining of methanol-fixed Hela cells using p53(Phospho-Ser15) Antibody TMAC-02995. 4. Immunofluorescence staining of methanol-fixed Hela cells using p53 (Phospho-Ser15) Antibody TMAC-02995. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 15 (P-L-S(p)-Q-E) derived from Human p53 |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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